Integrin associated proteins

被引:310
作者
Hemler, ME [1 ]
机构
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
关键词
D O I
10.1016/S0955-0674(98)80032-X
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Integrin cytoplasmic domains may interact directly with serveral different cytoskeletal proteins and intracellular signaling molecules. Also, integrins interact directly with other transmembrane structures, including transmembrane-4 superfamily (TM4SF) proteins. New evidence suggests that TM4SF proteins may act as linkers between extracellular integrin a chain domains and intracellular signaling molecules, such as phosphatidylinositol 4-kinase and protein kinase C.
引用
收藏
页码:578 / 585
页数:8
相关论文
共 86 条
[41]   Decreased resistance to bacterial infection and granulocyte defects in IAP-deficient mice [J].
Lindberg, FP ;
Bullard, DC ;
Caver, TE ;
Gresham, HD ;
Beaudet, AL ;
Brown, EJ .
SCIENCE, 1996, 274 (5288) :795-798
[42]   MOLECULAR-CLONING OF INTEGRIN-ASSOCIATED PROTEIN - AN IMMUNOGLOBULIN FAMILY MEMBER WITH MULTIPLE MEMBRANE-SPANNING DOMAINS IMPLICATED IN ALPHA-NU-BETA-3-DEPENDENT LIGAND-BINDING [J].
LINDBERG, FP ;
GRESHAM, HD ;
SCHWARZ, E ;
BROWN, EJ .
JOURNAL OF CELL BIOLOGY, 1993, 123 (02) :485-496
[43]   MEMBRANE COFACTOR PROTEIN (MCP OR CD46) - NEWEST MEMBER OF THE REGULATORS OF COMPLEMENT ACTIVATION GENE-CLUSTER [J].
LISZEWSKI, MK ;
POST, TW ;
ATKINSON, JP .
ANNUAL REVIEW OF IMMUNOLOGY, 1991, 9 :431-455
[44]  
Lu CF, 1997, J IMMUNOL, V159, P268
[45]   Integrin-mediated activation of focal adhesion kinase is independent of focal adhesion formation or integrin activation - Studies with activated and inhibitory beta(3) cytoplasmic domain mutants [J].
Lyman, S ;
Gilmore, A ;
Burridge, K ;
Gidwitz, S ;
White, GC .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (36) :22538-22547
[46]   The tetraspanin superfamily: Molecular facilitators [J].
Maecker, HT ;
Todd, SC ;
Levy, S .
FASEB JOURNAL, 1997, 11 (06) :428-442
[47]  
Mannion BA, 1996, J IMMUNOL, V157, P2039
[48]   INTEGRIN FUNCTION - MOLECULAR HIERARCHIES OF CYTOSKELETAL AND SIGNALING MOLECULES [J].
MIYAMOTO, S ;
TERAMOTO, H ;
COSO, OA ;
GUTKIND, JS ;
BURBELO, PD ;
AKIYAMA, SK ;
YAMADA, KM .
JOURNAL OF CELL BIOLOGY, 1995, 131 (03) :791-805
[49]   Phosphoinositide 3-OH kinase activates the β2 integrin adhesion pathway and induces membrane recruitment of cytohesin-1 [J].
Nagel, W ;
Zeitlmann, L ;
Schilcher, P ;
Geiger, C ;
Kolanus, J ;
Kolanus, W .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (24) :14853-14861
[50]   Identification of a novel calcium-binding protein that interacts with the integrin alpha(IIb) cytoplasmic domain [J].
Naik, UP ;
Patel, PM ;
Parise, LV .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (08) :4651-4654