Integrin associated proteins

被引:310
作者
Hemler, ME [1 ]
机构
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
关键词
D O I
10.1016/S0955-0674(98)80032-X
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Integrin cytoplasmic domains may interact directly with serveral different cytoskeletal proteins and intracellular signaling molecules. Also, integrins interact directly with other transmembrane structures, including transmembrane-4 superfamily (TM4SF) proteins. New evidence suggests that TM4SF proteins may act as linkers between extracellular integrin a chain domains and intracellular signaling molecules, such as phosphatidylinositol 4-kinase and protein kinase C.
引用
收藏
页码:578 / 585
页数:8
相关论文
共 86 条
[1]   ENGAGING CD19 OR TARGET OF AN ANTIPROLIFERATIVE ANTIBODY-1 ON HUMAN B-LYMPHOCYTES INDUCES BINDING OF B-CELLS TO THE INTERFOLLICULAR STROMA OF HUMAN TONSILS VIA INTEGRIN-ALPHA-4/BETA-1 AND FIBRONECTIN [J].
BEHR, S ;
SCHRIEVER, F .
JOURNAL OF EXPERIMENTAL MEDICINE, 1995, 182 (05) :1191-1199
[2]   A novel link between integrins, transmembrane-4 superfamily proteins (CD63 and CD81), and phosphatidylinositol 4-kinase [J].
Berditchevski, F ;
Tolias, KF ;
Wong, K ;
Carpenter, CL ;
Hemler, ME .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (05) :2595-2598
[3]   Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins) [J].
Berditchevski, F ;
Zutter, MM ;
Hemler, ME .
MOLECULAR BIOLOGY OF THE CELL, 1996, 7 (02) :193-207
[4]   Generation of monoclonal antibodies to integrin-associated proteins - Evidence that alpha(3)beta(1) complexes with EMMPRIN/basigin/OX47/M6 [J].
Berditchevski, F ;
Chang, S ;
Bodorova, J ;
Hemler, ME .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (46) :29174-29180
[5]   SPECIFIC ASSOCIATION OF CD63 WITH THE VLA-3 AND VLA-6 INTEGRINS [J].
BERDITCHEVSKI, F ;
BAZZONI, G ;
HEMLER, ME .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (30) :17784-17790
[6]  
BISWAS C, 1995, CANCER RES, V55, P434
[7]   DISTINCT CELLULAR FUNCTIONS MEDIATED BY DIFFERENT VLA INTEGRIN ALPHA-SUBUNIT CYTOPLASMIC DOMAINS [J].
CHAN, BM ;
KASSNER, PD ;
SCHIRO, JA ;
BYERS, HR ;
KUPPER, TS ;
HEMLER, ME .
CELL, 1992, 68 (06) :1051-1060
[8]   ICAP-1, a novel beta(1) integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta(1) integrin [J].
Chang, DD ;
Wong, C ;
Smith, H ;
Liu, J .
JOURNAL OF CELL BIOLOGY, 1997, 138 (05) :1149-1157
[9]   Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration [J].
Chapman, HA .
CURRENT OPINION IN CELL BIOLOGY, 1997, 9 (05) :714-724
[10]   Thrombospondin acts via integrin-associated protein to activate the platelet integrin alpha(IIb)beta(3) [J].
Chung, J ;
Gao, AG ;
Frazier, WA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (23) :14740-14746