N-Heterocyclic Carbene Palladium Catalyzed Regioselective Oxidative Trifluoroacetoxylation of Unactivated Methylene sp3 C-H Bonds in Linear Alkyl Esters

被引：39

作者：

Hou, Xiu-Feng ^{[1
]}

Wang, Ya-Nong ^{[1
]}

Goettker-Schnetmann, Inigo ^{[2
]}

机构：

[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China

[2] Univ Konstanz, Dept Chem, D-78457 Constance, Germany

来源：

ORGANOMETALLICS | 2011年 / 30卷 / 21期

基金：

美国国家科学基金会;

关键词：

ALKANE DEHYDROGENATION; PINCER COMPLEXES; METAL-COMPLEXES; ACTIVATION; FUNCTIONALIZATION; INSERTION; HYDROCARBONS; OXYGENATION; ARYLATION; RHODIUM;

D O I：

10.1021/om200484g

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Several N-heterocyclic carbene palladium catalyzed oxidation of nonactivated sp(3) C-H bonds in linear primary and secondary trifluoroacetic acid esters have been developed. A high selectivity for the oxidation of the omega-1 carbon atom in trifluoroacetic acid n-propyl to n-octyl esters was realized by an appropriate choice of N-heterocyclic carbene palladium complexes.

引用

页码：6053 / 6056

页数：4

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