Preliminary evidence of within-subject changes in gray matter density associated with remission of bipolar depression

被引：10

作者：

Brooks, John O., III ^{[1
]}

Foland-Ross, Lara C. ^{[2
]}

Thompson, Paul M. ^{[2
]}

Altshuler, Lori L. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Semel Inst Neurosci & Human Behav, Los Angeles, CA USA

[2] UCLA Sch Med, Lab Neurolmaging, Dept Neurol, Los Angeles, CA USA

来源：

PSYCHIATRY RESEARCH-NEUROIMAGING | 2011年 / 193卷 / 01期

关键词：

Bipolar disorder; Depression; Magnetic resonance imaging; MRI; Prefrontal; VOXEL-BASED MORPHOMETRY; ORBITOFRONTAL CORTEX; RATING-SCALE; DISORDER; ABNORMALITIES; METABOLISM; VOLUME; MRI;

D O I：

10.1016/j.pscychresns.2010.12.012

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A preliminary within-subjects MRI study of seven patients with a diagnosis of bipolar I disorder revealed that, compared to remission, depression was associated with gray matter density increases in subgenual prefrontal cortex, parahippocampal gyrus, and inferior temporal gyri. Decreases were observed in superior and inferior frontal gyri and anterior cingulate. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

引用

页码：53 / 55

页数：3

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