Use of adipose tissue in regenerative medicine

被引：10

作者：

Casteilla, L. ^{[1
,2
]}

Planat-Benard, V. ^{[1
,2
]}

Bourin, P. ^{[1
,2
,3
]}

Laharrague, P. ^{[1
,2
]}

Cousin, B. ^{[1
,2
]}

机构：

[1] CNRS, INSERM, UMR UPS EFS 5273, U103, F-31432 Toulouse, France

[2] Univ Toulouse, UMR UPS 5241, F-31432 Toulouse, France

[3] EFS PM, Lab Therapie Cellulaire, F-31300 Toulouse, France

来源：

TRANSFUSION CLINIQUE ET BIOLOGIQUE | 2011年 / 18卷 / 02期

关键词：

Adipose tissue; Stem cell; Stroma; Cell therapy; MESENCHYMAL STEM-CELLS; THERAPY POSITION STATEMENT; COMPLEX PERIANAL FISTULA; UMBILICAL-CORD BLOOD; STROMAL CELLS; BONE-MARROW; MYOCARDIAL-INFARCTION; IN-VIVO; IMMUNOSUPPRESSIVE PROPERTIES; INTERNATIONAL-SOCIETY;

D O I：

10.1016/j.tracli.2011.01.008

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Adipose tissue is abundant and well known for its involvement in obesity and associated metabolic disorders. Its uses in regenerative medicine recently attracted many investigators, as large amounts of this tissue can be easily obtained using liposuction and it contains several populations of immature cells. The largest pool of such cells corresponds to immature stromal cells, called adipose-derived stromal cells (ADSCs). These cells are purified after proteolytic digestion of adipose tissue and selection by an adherent step. ADSCs display many common features with mesenchymal stem cells derived from bone marrow, including paracrine activity, but with some specific features, among which a greater angiogenic potential. This potential is now investigating at clinical level to treat critical ischemic hindlimb by autologous cells. Other potentials are also investigated and the treatment of fistula associated or not with Crohn's disease is reaching now phase III level. (C) 2011 Elsevier Masson SAS. All rights reserved.

引用

页码：124 / 128

页数：5

共 52 条

[1] Cell-assisted lipotransfer for cosmetic breast augmentation: Supportive use of adipose-derived stem/stromal cells [J].

Altman, Andrew M. ;

Alt, Eckhard U. .

AESTHETIC PLASTIC SURGERY, 2008, 32 (01) :56-57

[2] Composite Cell Sheets A Further Step Toward Safe and Effective Myocardial Regeneration by Cardiac Progenitors Derived From Embryonic Stem Cells [J].

Bel, Alain ;

Planat-Bernard, Valerie ;

Saito, Atsuhiro ;

Bonnevie, Lionel ;

Bellamy, Valerie ;

Sabbah, Laurent ;

Bellabas, Linda ;

Brinon, Benjamin ;

Vanneaux, Valerie ;

Pradeau, Pascal ;

Peyrard, Severine ;

Larghero, Jerome ;

Pouly, Julia ;

Binder, Patrice ;

Garcia, Sylvie ;

Shimizu, Tatsuya ;

Sawa, Yoshiki ;

Okano, Teruo ;

Bruneval, Patrick ;

Desnos, Michel ;

Hagege, Albert A. ;

Casteilla, Louis ;

Puceat, Michel ;

Menasche, Philippe .

CIRCULATION, 2010, 122 (11) :S118-S123

[3] Mesenchymal stem cells as trophic mediators [J].

Caplan, Arnold I. ;

Dennis, James E. .

JOURNAL OF CELLULAR BIOCHEMISTRY, 2006, 98 (05) :1076-1084

[4]

Casteilla L, 2011, METHODS MOL BIOL, V702, P269, DOI 10.1007/978-1-61737-960-4_20

[5] Adipose-Derived Mesenchymal Stem Cells Ameliorate Chronic Experimental Autoimmune Encephalomyelitis [J].

Constantin, Gabriela ;

Marconi, Silvia ;

Rossi, Barbara ;

Angiari, Stefano ;

Calderan, Laura ;

Anghileri, Elena ;

Gini, Beatrice ;

Bach, Simone Dorothea ;

Martinello, Marianna ;

Bifari, Francesco ;

Galie, Mirco ;

Turano, Ermanna ;

Budui, Simona ;

Sbarbati, Andrea ;

Krampera, Mauro ;

Bonetti, Bruno .

STEM CELLS, 2009, 27 (10) :2624-2635

[6] Human subcutaneous adipose cells support complete differentiation but not self-renewal of hematopoietic progenitors [J].

Corre, Jill ;

Barreau, Corinne ;

Cousin, Beatrice ;

Chavoin, Jean-Pierre ;

Caton, David ;

Fournial, Gerard ;

Penicaud, Luc ;

Casteilla, Louis ;

Laharrague, Patrick .

JOURNAL OF CELLULAR PHYSIOLOGY, 2006, 208 (02) :282-288

[7] Adult Stromal Cells Derived from Human Adipose Tissue Provoke Pancreatic Cancer Cell Death both In Vitro and In Vivo [J].

Cousin, Beatrice ;

Ravet, Emmanuel ;

Poglio, Sandrine ;

De Toni, Fabienne ;

Bertuzzi, Melanie ;

Lulka, Hubert ;

Touil, Ismahane ;

Andre, Mireille ;

Grolleau, Jean-Louis ;

Peron, Jean-Marie ;

Chavoin, Jean-Pierre ;

Bourin, Philippe ;

Penicaud, Luc ;

Casteilla, Louis ;

Buscail, Louis ;

Cordelier, Pierre .

PLOS ONE, 2009, 4 (07)

[8] A perivascular origin for mesenchymal stem cells in multiple human organs [J].

Crisan, Mihaela ;

Yap, Solomon ;

Casteilla, Louis ;

Chen, Chien-Wen ;

Corselli, Mirko ;

Park, Tea Soon ;

Andriolo, Gabriella ;

Sun, Bin ;

Zheng, Bo ;

Zhang, Li ;

Norotte, Cyrille ;

Teng, Pang-Ning ;

Traas, Jeremy ;

Schugar, Rebecca ;

Deasy, Bridget M. ;

Badylak, Stephen ;

Buehring, Hans-Joerg ;

Giacobino, Jean-Paul ;

Lazzari, Lorenza ;

Huard, Johnny ;

Peault, Bruno .

CELL STEM CELL, 2008, 3 (03) :301-313

[9] Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement [J].

Dominici, M. ;

Le Blanc, K. ;

Mueller, I. ;

Slaper-Cortenbach, I. ;

Marini, F. C. ;

Krause, D. S. ;

Deans, R. J. ;

Keating, A. ;

Prockop, D. J. ;

Horwitz, E. M. .

CYTOTHERAPY, 2006, 8 (04) :315-317

[10] Cell Therapy Based on Adipose Tissue-Derived Stromal Cells Promotes Physiological and Pathological Wound Healing [J].

Ebrahimian, T. G. ;

Pouzoulet, F. ;

Squiban, C. ;

Buard, V. ;

Andre, M. ;

Cousin, B. ;

Gourmelon, P. ;

Benderitter, M. ;

Casteilla, L. ;

Tamarat, R. .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2009, 29 (04) :503-510

← 1 2 3 4 5 6 →