Cluster headache patients are not affected by restless legs syndrome: An observational study

被引：7

作者：

Florindo, D'Onofrio ^{[2
]}

Daniela, Cologno ^{[1
]}

Giulio, Cicarelli ^{[2
]}

Vittorio, Petretta ^{[2
]}

Gabriella, Marsala ^{[1
]}

Vincenzo, Tullo ^{[3
]}

Eliana, Mea ^{[3
]}

Gerardo, Casucci ^{[4
]}

Gennaro, Bussone ^{[3
]}

机构：

[1] Azienda Osped Univ Osped Riuniti, Inst Clin Neurophysiol, Dept Neurosci, I-71100 Foggia, Italy

[2] Hlth Unit SG Moscati, Neurol Unit, Avellino, Italy

[3] Fdn IRCCS Neurol Inst C Besta, Milan, Italy

[4] S Francesco Nursing Home, Telese Terme, BN, Italy

来源：

CLINICAL NEUROLOGY AND NEUROSURGERY | 2011年 / 113卷 / 04期

关键词：

Cluster headache; Restless legs syndrome; Prevalence; Dopamine; Melatonin; MELATONIN; EPIDEMIOLOGY; PREVALENCE; SYMPTOMS; MIGRAINE; NEURONS;

D O I：

10.1016/j.clineuro.2010.12.006

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: To investigate the presence of Restless Legs Syndrome (RLS) in Cluster Headache (CH) patients compared to headache-free controls. Design and setting: Cross-sectional case-control study of CH patients presenting at tertiary headache centers over the period January-December 2008. Patients and participants: Fifty consecutive patients (6 women and 44 men) of mean age of 39.7 year (standard deviation 10.9) with episodic or chronic CH diagnosed according to ICHD-II criteria and 50 headache-free subjects matched by age and sex were recruited. Results: None of the CH patients had RLS. Six (12%) headache-free controls had RLS. Conclusions: Our data indicate no probable relationship between CH and RLS. However, since both conditions have a circadian rhythm and are associated with altered melatonin secretion, we conjecture that reduced nocturnal melatonin in CH likely allows sustained dopaminergic activity which could be protective against RLS in CH patients. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：308 / 310

页数：3

共 28 条

[1] Melatonin: effects on dopaminergic and serotonergic neurons of the caudate nucleus of the striatum of male Syrian hamsters
Alexiuk, N. A. M.
Vriend, J.
[J]. JOURNAL OF NEURAL TRANSMISSION, 2007, 114 (05) : 549 - 554
[2] Physician-diagnosed restless legs syndrome in a large sample of primary medical care patients in western Europe: Prevalence and characteristics
Allen, Richard P.
Stillman, Paul
Myers, Andrew J.
[J]. SLEEP MEDICINE, 2010, 11 (01) : 31 - 37
[3] Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology - A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health
Allen, RP
Picchietti, D
Hening, WA
Trenkwalder, C
Walters, AS
Montplaisi, J
[J]. SLEEP MEDICINE, 2003, 4 (02) : 101 - 119
[4] [Anonymous], 2005, INT CLASSIFICATION S
[5] PSYCHOMETRIC PROPERTIES OF THE BECK DEPRESSION INVENTORY - 25 YEARS OF EVALUATION
BECK, AT
STEER, RA
GARBIN, MG
[J]. CLINICAL PSYCHOLOGY REVIEW, 1988, 8 (01) : 77 - 100
[6] Melatonin inhibits 6-hydroxydopamine production in the brain to protect against experimental parkinsonism in rodents
Borah, Anupom
Mohanakumar, Kochupurackal P.
[J]. JOURNAL OF PINEAL RESEARCH, 2009, 47 (04) : 293 - 300
[7] Cluster headache: from treatment to pathophysiology
Bussone, Gennaro
[J]. NEUROLOGICAL SCIENCES, 2008, 29 (Suppl 1) : S1 - S6
[8] Chen PK, 2010, J NEUROL NEUROSUR PS, V81, P524, DOI 10.1136/jnnp.2009.191684
[9] High prevalence of Dopaminergic Premonitory Symptoms in migraine patients with Restless Legs Syndrome: a pathogenetic link?
Cologno, Daniela
Cicarelli, Giulio
Petretta, Vittorio
d'Onofrio, Florindo
Bussone, Gennaro
[J]. NEUROLOGICAL SCIENCES, 2008, 29 (Suppl 1) : S166 - S168
[10] Restless legs syndrome and primary headaches: a clinical study
d'Onofrio, Florindo
Bussone, Gennaro
Cologno, Daniela
Petretta, Vittorio
Buzzi, Maria Grazia
Tedeschi, Gioacchino
Bonavita, Vincenzo
Cicarelli, Giulio
[J]. NEUROLOGICAL SCIENCES, 2008, 29 (Suppl 1) : S169 - S172

← 1 2 3 →