Transperitoneal Enucleation of a Kidney Transplant Allograft Renal Cell Carcinoma

被引:2
作者
Sarantitis, Ioannis [1 ]
Pararajasingam, Ravi [1 ]
Forgacs, Bence [1 ]
Denley, Helen [2 ]
Wood, Grahame [3 ]
Augustine, Titus [1 ,4 ]
机构
[1] Manchester Royal Infirm, Dept Renal & Pancreas Transplantat, Oxford Rd, Manchester M13 9WL, Lancs, England
[2] Manchester Royal Infirm, Dept Histopathol, Manchester, Lancs, England
[3] Salford Royal NHS Fdn Trust, Dept Nephrol, Salford, Lancs, England
[4] Univ Manchester, Inst Human Dev, Manchester, Lancs, England
关键词
Cancer; De novo; Immunosuppression; mTOR; Sirolimus; NEPHRON-SPARING SURGERY; CANCER; TUMORS; RISK;
D O I
10.6002/ect.2016.0037
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
Development of malignancy after solid-organ trans plant is a well-known long-term complication of immunosuppressive therapy. Thus far, there are no specific oncologic recommendations regarding management of de novo tumors in transplanted kidneys. Here, we present the case of a 63-year-old male patient who developed a de novo renal cell carcinoma 6 years after the transplant procedure. The patient underwent nephron-sparing surgery with transperitoneal enucleation of the tumor. We discuss the decision-making process and the operative challenges that we faced. We conclude that this technique should be considered as a therapeutic strategy for selected patients so that transplant nephrectomy can be avoided.
引用
收藏
页码:614 / 616
页数:3
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