Acute kidney injury, fluid balance and risks of intraventricular hemorrhage in premature infants

被引：8

作者：

Adcock, Brittnea ^{[1
]}

Carpenter, Sean ^{[2
]}

Bauer, John ^{[2
]}

Giannone, Peter ^{[2
]}

Schadler, Aric ^{[2
]}

Chishti, Aftab ^{[2
]}

Hanna, Mina ^{[2
]}

机构：

[1] East Tennessee State Univ, Johnson City, TN 37614 USA

[2] Univ Kentucky, Lexington, KY USA

来源：

JOURNAL OF PERINATOLOGY | 2020年 / 40卷 / 09期

关键词：

OUTCOMES;

D O I：

10.1038/s41372-020-0613-5

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective Evaluate association between fluid balance and intraventricular hemorrhage (IVH). Study design Retrospective review of infants Results Infants with acute kidney injury (AKI) had a 2.4-fold increased risk of IVH (OR 2.38, 95% CI 1.46-3.87) and a 3.5-fold increased risk of severe IVH (OR 3.45, 95% CI 1.98-6.04). Infants above birthweight on day 4 had a 1.9-fold increased risk of IVH (OR 1.86, 95% CI 1.05-3.27) and a 2.0-fold increased risk of severe IVH (OR 1.96, 95% CI 1.03-3.74). When controlling for confounding factors, infants with AKI or above birthweight on day 4 had a 4.6-fold (aOR 4.60, 95% CI 1.80-11.78) and 3.0-fold (aOR 2.96, 95% CI 1.01-8.65) increased risk of severe IVH, respectively. Conclusion Infants with AKI during the first week of life had a higher association of severe IVH even after controlling for confounding factors.

引用

页码：1296 / 1300

页数：5

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