Dynamic Contrast-Enhanced Ultrasound for Quantification of Tissue Perfusion

被引：78

作者：

Froehlich, Eckhart ^{[1
]}

Muller, Reinhold ^{[2
,3
]}

Cui, Xin-Wu ^{[4
,5
]}

Schreiber-Dietrich, Dagmar ^{[4
,5
]}

Dietrich, Christoph F. ^{[4
,5
]}

机构：

[1] Univ Ulm, Acad Teaching Hosp, Dept Internal Med 1, Karl Olga Krankenhaus Stuttgart, D-89069 Ulm, Germany

[2] Trop Hlth Solut Pty Ltd, Townsville, Qld, Australia

[3] James Cook Univ, Anton Breinl Ctr, Townsville, Qld 4811, Australia

[4] Zhengzhou Univ, Affiliated Hosp 1, Sino German Res Ctr Ultrasound Med, Zhengzhou 450052, Peoples R China

[5] Univ Wurzburg, Acad Teaching Hosp, Caritas Krankenhaus Bad Mergentheim, Dept Internal Med 2, Bad Mergentheim, Germany

来源：

JOURNAL OF ULTRASOUND IN MEDICINE | 2015年 / 34卷 / 02期

关键词：

bolus protocol; guidelines; infusion protocol; perfusion quantification; therapy monitoring; ultrasound contrast agents; vascular ultrasound; CLINICAL-PRACTICE RECOMMENDATIONS; GASTROINTESTINAL STROMAL TUMORS; CARCINOMA EARLY EVALUATION; ULTRASONOGRAPHY DCE-US; RENAL-CELL CARCINOMA; HEPATOCELLULAR-CARCINOMA; LIVER METASTASES; BLOOD-FLOW; ANTIANGIOGENIC TREATMENT; TRANSRECTAL ULTRASOUND;

D O I：

10.7863/ultra.34.2.179

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

Dynamic contrast-enhanced ultrasound (US) imaging, a technique that uses microbubble contrast agents with diagnostic US, has recently been technically summarized and reviewed by a European Federation of Societies for Ultrasound in Medicine and Biology position paper. However, the practical applications of this imaging technique were not included. This article reviews and discusses the published literature on the clinical use of dynamic contrast-enhanced US. This review finds that dynamic contrast-enhanced US imaging is the most sensitive cross-sectional real-time method for measuring the perfusion of parenchymatous organs noninvasively. It can measure parenchymal perfusion and therefore can differentiate between benign and malignant tumors. The most important routine clinical role of dynamic contrast-enhanced US is the prediction of tumor responses to chemotherapy within a very short time, shorter than using Response Evaluation Criteria in Solid Tumors criteria. Other applications found include quantifying the hepatic transit time, diabetic kidneys, transplant grafts, and Crohn disease. In addition, the problems involved in using dynamic contrast-enhanced US are discussed.

引用

页码：179 / 196

页数：18

共 88 条

[1]

Argalia G, 2002, Radiol Med, V103, P407

[2] QUANTIFICATION OF TUMOR MICROVASCULARITY WITH RESPIRATORY GATED CONTRAST ENHANCED ULTRASOUND FOR MONITORING THERAPY [J].

Averkiou, Michalakis ;

Lampaskis, Marios ;

Kyriakopoulou, Konstantina ;

Skarlos, Dimosthenis ;

Klouvas, Georgios ;

Strouthos, Costas ;

Leenz, Edward .

ULTRASOUND IN MEDICINE AND BIOLOGY, 2010, 36 (01) :68-77

[3]

Barnard S, 2008, SAMJ S AFR MED J, V98, P386

[4] Contrast-enhanced ultrasound in the characterisation of breast masses: utility of quantitative analysis in comparison with MRI [J].

Caproni, Natalia ;

Marchisio, Francesca ;

Pecchi, Annarita ;

Canossi, Barbara ;

Battista, Rachele ;

D'Alimonte, Piero ;

Torricelli, Pietro .

EUROPEAN RADIOLOGY, 2010, 20 (06) :1384-1395

[5] Characterization of focal liver lesions: comparative study of contrast-enhanced ultrasound versus spiral computed tomography [J].

Catala, V. ;

Nicolau, C. ;

Vilana, R. ;

Pages, M. ;

Bianchi, L. ;

Sanchez, M. ;

Bru, C. .

EUROPEAN RADIOLOGY, 2007, 17 (04) :1066-1073

[6] Intrahepatic cholangiocarcinoma and hepatocellular carcinoma: differential diagnosis with contrast-enhanced ultrasound [J].

Chen, Li-Da ;

Xu, Hui-Xiong ;

Xie, Xiao-Yan ;

Xie, Xiao-Hua ;

Xu, Zuo-Feng ;

Liu, Guang-Jian ;

Wang, Zhu ;

Lin, Man-Xia ;

Lu, Ming-De .

EUROPEAN RADIOLOGY, 2010, 20 (03) :743-753

[7] Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS) -: Update 2008 [J].

Claudon, M. ;

Cosgrove, D. ;

Albrecht, T. ;

Bolondi, L. ;

Bosio, M. ;

Calliada, F. ;

Correas, J. -M. ;

Darge, K. ;

Dietrich, C. ;

D'Onofrio, M. ;

Evans, D. H. ;

Filice, C. ;

Greiner, L. ;

Jaeger, K. ;

de Jong, N. ;

Leen, E. ;

Lencioni, R. ;

Lindsell, D. ;

Martegani, A. ;

Meairs, S. ;

Nolsoe, C. ;

Piscaglia, F. ;

Ricci, P. ;

Seidel, G. ;

Skjoldbye, B. ;

Solbiati, L. ;

Thorelius, L. ;

Tranquart, F. ;

Weskott, H. P. ;

Whittingham, T. .

ULTRASCHALL IN DER MEDIZIN, 2008, 29 (01) :28-44

[8] Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) in the Liver - Update 2012 A WFUMB-EFSUMB Initiative in Cooperation With Representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS [J].

Claudon, M. ;

Dietrich, C. F. ;

Choi, B. I. ;

Cosgrove, D. O. ;

Kudo, M. ;

Nolsoe, C. P. ;

Piscaglia, F. ;

Wilson, S. R. ;

Barr, R. G. ;

Chammas, M. C. ;

Chaubal, N. G. ;

Chen, M. -H. ;

Clevert, D. A. ;

Correas, J. M. ;

Ding, H. ;

Forsberg, F. ;

Fowlkes, J. B. ;

Gibson, R. N. ;

Goldberg, B. B. ;

Lassau, N. ;

Leen, E. L. S. ;

Mattrey, R. F. ;

Moriyasu, F. ;

Solbiati, L. ;

Weskott, H. -P. ;

Xu, H. -X. .

ULTRASCHALL IN DER MEDIZIN, 2013, 34 (01) :11-29

[9] Effect of angiosonography to monitor response during imatinib treatment in patients with metastatic gastrointestinal stromal tumors [J].

De Giorgi, U ;

Aliberti, C ;

Benea, G ;

Conti, M ;

Marangolo, M .

CLINICAL CANCER RESEARCH, 2005, 11 (17) :6171-6176

[10] An EFSUMB Introduction into Dynamic Contrast-Enhanced Ultrasound (DCE-US) for Quantification of Tumour Perfusion [J].

Dietrich, C. F. ;

Averkiou, M. A. ;

Correas, J. -M. ;

Lassau, N. ;

Leen, E. ;

Piscaglia, F. .

ULTRASCHALL IN DER MEDIZIN, 2012, 33 (04) :344-351

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