Accuracy of bedside antigen tests in the diagnosis of new influenza A/H1N1v infection

被引:10
作者
Bellmann-Weiler, R. [1 ]
Beikircher, B. [1 ]
Kurz, K. [1 ]
Theurl, I. [1 ]
Weiss, G. [1 ]
机构
[1] Med Univ Innsbruck, Dept Internal Med, Clin Immunol & Infect Dis, Innsbruck, Austria
关键词
Bedside test; H1N1; influenza A; real-time PCR; A H1N1 VIRUS; PERFORMANCE; FLU;
D O I
10.1111/j.1469-0691.2010.03235.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
P>To evaluate the clinical reliability of two rapid influenza detection tests (RIDTs), we analyzed 107 specimens from patients with clinically suspected pandemic influenza A/H1N1v by these tests as well as by real-time PCR as a standard. Both RIDTs had a moderate sensitivity (28-32%), a high specificity (93-99%) and a negative predictive value of 80%. These results will impact on the clinical management and isolation precautions in patients with suspected infection. Although a positive RITD is mostly confirmatory, a negative result in the presence of high clinical likelihood of infection should be interpreted with caution and be re-evaluated by PCR.
引用
收藏
页码:235 / 237
页数:3
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