Circulating miRNome profiling data in Behcet's syndrome

被引：6

作者：

Bagni, Giacomo ^{[1
]}

Emmi, Giacomo ^{[1
,2
]}

Lastraioli, Elena ^{[1
]}

Di Patti, Francesca ^{[3
,4
]}

Silvestri, Elena ^{[2
]}

Guerriero, Angela ^{[1
]}

Pillozzi, Serena ^{[1
]}

Niccolai, Elena ^{[1
]}

Amedei, Amedeo ^{[1
,2
]}

Emmi, Lorenzo ^{[5
]}

Prisco, Domenico ^{[1
]}

Arcangeli, Annarosa ^{[1
,4
]}

机构：

[1] Univ Florence, Dept Expt & Clin Med, Florence, Italy

[2] Clin Azienda Osped Univ Careggi, SOD Interdisciplinary Internal Med Behcet Ctr & L, Florence, Italy

[3] Univ Florence, Dept Phys, Florence, Italy

[4] Ctr Study Complex Dynam CSDC, Florence, Italy

[5] Univ Florence, Dept Neurosci Psychol Drug Res & Child Hlth, Florence, Italy

来源：

DATA IN BRIEF | 2021年 / 38卷

关键词：

microRNA; Circulating miRNAs; Behcet; Microarray; Biomarker;

D O I：

10.1016/j.dib.2021.107435

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We conducted a screening analysis to assess the presence of a characteristic extracellular circulating microRNAs (ci-miRNAs) profile in Behcet's syndrome (BS). Total RNA was extracted from platelets-free plasma (PFP) samples obtained from 16 BS patients and 18 healthy controls. Ci-miRNAs profiling was conducted by using dedicated Agilent microarray hybridization and data extraction technology. Statistical analysis of data extracted from microarray scanning revealed the deregulation of 36 ci-miRNAs, which turned out be differentially expressed between BS patients and healthy controls. Detailed experimental methods and data analysis were described here. The raw and normalized microarray data were deposited into Gene Expression Omnibus (GEO) under accession number GSE145191. (C) 2021 Published by Elsevier Inc.

引用

页数：8

共 6 条

[1] Behcet: the syndrome [J].

Bettiol, Alessandra ;

Prisco, Domenico ;

Emmi, Giacomo .

RHEUMATOLOGY, 2020, 59 :101-107

[2] Assessing sample and miRNA profile quality in serum and plasma or other biofluids [J].

Blondal, Thorarinn ;

Nielsen, Soren Jensby ;

Baker, Adam ;

Andreasen, Ditte ;

Mouritzen, Peter ;

Teilum, Maria Wrang ;

Dahlsveen, Ina K. .

METHODS, 2013, 59 (01) :S1-S6

[3] The International Criteria for Behcet's Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria [J].

Davatchi, F. ;

Assaad-Khalil, S. ;

Calamia, K. T. ;

Crook, J. E. ;

Sadeghi-Abdollahi, B. ;

Schirmer, M. ;

Tzellos, T. ;

Zouboulis, C. C. ;

Akhlagi, M. ;

Al-Dalaan, A. ;

Alekberova, Z. S. ;

Ali, A. A. ;

Altenburg, A. ;

Arromdee, E. ;

Baltaci, M. ;

Bastos, M. ;

Benamour, S. ;

Ben Ghorbel, I. ;

Boyvat, A. ;

Carvalho, L. ;

Chen, W. ;

Ben-Chetrit, E. ;

Chams-Davatchi, C. ;

Correia, J. A. ;

Crespo, J. ;

Dias, C. ;

Dong, Y. ;

Paixao-Duarte, F. ;

Elmuntaser, K. ;

Elonakov, A. V. ;

Grana Gil, J. ;

Haghdoost, A-A. ;

Hayani, R. M. ;

Houman, H. ;

Isayeva, A. R. ;

Jamshidi, A. R. ;

Kaklamanis, P. ;

Kumar, A. ;

Kyrgidis, A. ;

Madanat, W. ;

Nadji, A. ;

Namba, K. ;

Ohno, S. ;

Olivieri, I. ;

Vaz Patto, J. ;

Pipitone, N. ;

de Queiroz, M. V. ;

Ramos, F. ;

Resende, C. ;

Rosa, C. M. .

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2014, 28 (03) :338-347

[4] Changes in the microRNA expression profile during blood storage [J].

Haberberger, Anna ;

Kirchner, Benedikt ;

Riedmaier, Irmgard ;

Henschler, Reinhard ;

Wichmann, Christian ;

Buhmann, Raymund ;

Pfaffl, Michael W. .

BMJ OPEN SPORT & EXERCISE MEDICINE, 2018, 4 (01)

[5] Pre-processing and differential expression analysis of Agilent microRNA arrays using the AgiMicroRna Bioconductor library [J].

Lopez-Romero, Pedro .

BMC GENOMICS, 2011, 12

[6] Methodological challenges in utilizing miRNAs as circulating biomarkers [J].

Moldovan, Leni ;

Batte, Kara E. ;

Trgovcich, Joanne ;

Wisler, Jon ;

Marsh, Clay B. ;

Piper, Melissa .

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2014, 18 (03) :371-390

← 1 →