The inflammatory reaction during chronic venous disease of lower limbs

被引:17
|
作者
Ojdana, Dominika [1 ]
Safiejko, Kamil [2 ]
Lipska, Alina [3 ]
Sacha, Pawel [1 ]
Wieczorek, Piotr [1 ]
Radziwon, Piotr [3 ]
Dadan, Jacek [2 ]
Tryniszewska, Elzbieta [1 ]
机构
[1] Med Univ Bialystok, Dept Microbiol Diagnost, PL-15269 Bialystok, Poland
[2] Med Univ Bialystok, Dept Gen & Endocrinol Surg 1, PL-15269 Bialystok, Poland
[3] Reg Ctr Transfus Med Bialystok, Bialystok, Poland
关键词
chronic venous disease; inflammatory process; leukocytes; MAST-CELL INFILTRATION; VARICOSE-VEINS; INSUFFICIENCY; ENDOTHELIUM; ACTIVATION; COLLAGEN; MATRIX; HISTOPATHOLOGY; EPIDEMIOLOGY; SYMPTOMS;
D O I
10.2478/v10042-009-0029-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Chronic venous disease (CVD) is an insufficiency of distal veins caused by their partial or total obstruction, endothelial distension and functional disorders. Chronic venous disease of lower limbs is common problem and affects millions of people. In this article we suggest that inflammatory process is involved in the structural remodeling in venous valves and in the venous wall, leading to valvular incompetence and the development of varicose veins.
引用
收藏
页码:185 / 189
页数:5
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