A Facile and Efficient Synthesis of 3-Aryloxazolidin-2-ones from Isocyanates and Epoxides Promoted by MgI2 Etherate

被引:20
|
作者
Zhang, Xingxian [1 ]
Chen, Wei [1 ]
Zhao, Chengfeng [1 ]
Li, Cheng [1 ]
Wu, Xiang [1 ]
Chen, Wei Z. [1 ]
机构
[1] Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310032, Zhejiang, Peoples R China
关键词
Epoxide; isocyanate; MgI2; etherate; oxazolidinone; CATALYZED CYCLOADDITION; OXAZOLIDINONES; 2-OXAZOLIDONES; ALLYLATION; ALDEHYDES; OXIRANES;
D O I
10.1080/00397910903470525
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
We described a mild and efficient procedure for the synthesis of 3-aryloxazolidin-2-ones via the cycloaddition of isocyanates with epoxides in the presence of MgI2 etherate (MgI2 center dot(OEt2)n) in good yields.
引用
收藏
页码:3654 / 3659
页数:6
相关论文
共 50 条
  • [1] An Efficient and Highly Regioselective Cycloaddition of Aryl Isocyanates with Oxiranes Promoted by MgI2 Etherate
    Zhang, Xingxian
    Chen, Wei
    CHEMISTRY LETTERS, 2010, 39 (05) : 527 - 529
  • [2] Highly efficient synthesis of homoallylamines from aldimines with allylstannane promoted by MgI2 etherate
    Zhang, Xingxian
    Hu, Shenghui
    Shi, Junchen
    JOURNAL OF CHEMICAL RESEARCH, 2010, (06) : 336 - 339
  • [3] MgI2 etherate-promoted allylation of aldehydes:: Simple and efficient synthesis of homoallylic alcohols
    Zhang, Xingxian
    LETTERS IN ORGANIC CHEMISTRY, 2007, 4 (04) : 246 - 248
  • [4] An efficient and convenient aldol addition of acyldiazomethane with aldehydes promoted by MgI2 etherate
    Xie, Xiaoqiang
    Qi, Weipeng
    Sun, Xinzhe
    Zhang, Xingxian
    MAIN GROUP METAL CHEMISTRY, 2017, 40 (3-4) : 87 - 91
  • [5] MgI2 etherate-catalysed Strecker reaction: a facile and efficient synthesis of α-aminonitriles from aldimines and trimethylsilyl cyanide
    Lu, Yongping
    Wang, Yanping
    Zhang, Xingxian
    JOURNAL OF CHEMICAL RESEARCH, 2013, (11) : 709 - 711
  • [6] An efficient direct-aldol addition of methyl ketones with aldehydes promoted by MgI2 etherate
    Liu, Yingshuai
    Shen, Hangzhou
    Zhang, Xingxian
    MAIN GROUP METAL CHEMISTRY, 2012, 35 (3-4) : 111 - 115
  • [7] MgI2 Etherate-Catalyzed Three-Component Allylation: A Facile and Efficient Synthesis of Homoallylic Amines
    Zhang, Xingxian
    Ye, Saisai
    Hu, Shenghui
    LETTERS IN ORGANIC CHEMISTRY, 2011, 8 (06) : 427 - 430
  • [8] Mild and efficient allylation of aldehydes with allyltributylstannane promoted by MgI2•(OEt)n etherate
    Zhang, Xingxian
    SYNLETT, 2008, (01) : 65 - 68
  • [9] An efficient cyanosilylation of aldehydes with trimethylsilyl cyanide catalysed by MgI2 etherate
    Wang, Yanping
    Feng, Meiling
    Liu, Yingshuai
    Zhang, Xingxian
    JOURNAL OF CHEMICAL RESEARCH, 2012, (10) : 566 - 567
  • [10] An efficient three-component synthesis of homoallylic amines catalysed by MgI2 etherate
    Wang, Yanping
    Liu, Yingshuai
    Hu, Shenghui
    Zhang, Xingxian
    JOURNAL OF CHEMICAL RESEARCH, 2012, (01) : 21 - 24