Staphylococcus aureus: A Continuously Evolving and Formidable Pathogen in the Neonatal Intensive Care Unit

被引：19

作者：

Carey, Alison J. ^{[1
]}

Long, Sarah S. ^{[2
]}

机构：

[1] St Christophers Hosp Children, Div Neonatol, Philadelphia, PA 19134 USA

[2] St Christophers Hosp Children, Div Infect Dis, Philadelphia, PA 19134 USA

来源：

CLINICS IN PERINATOLOGY | 2010年 / 37卷 / 03期

关键词：

Staphylococcus aureus; MRSA; MSSA; Neonates; NURSERY-ACQUIRED INFECTION; METHICILLIN-RESISTANT; BACTERIAL INTERFERENCE; RISK-FACTORS; EPIDEMIOLOGIC CHARACTERISTICS; NASAL CARRIAGE; ONSET SEPSIS; SCCMEC TYPE; VANCOMYCIN; COLONIZATION;

D O I：

10.1016/j.clp.2010.05.002

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Staphylococcus aureus is a continuously evolving and formidable pathogen that has been a problem for both healthy and sick neonates for decades. Much focus over the past 20 years has been on hospital-associated methicillinresistant S aureus (HA-MRSA); however, a global epidemic because of virulent community-associated MRSA (CA-MRSA) that has no "fitness cost" for carrying antibiotic-resistance genes has moved into neonatal intensive care units (NICUs). Recently, methicillin-susceptible S aureus has adopted some of the virulence factors of CA-MRSA and is an increasingly common cause of hospital-acquired infections in NICUs. This article reviews the changing epidemiology, clinical manifestations, and treatment of S aureus in neonates.

引用

页码：535 / +

页数：13

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