Staphylococcus aureus: A Continuously Evolving and Formidable Pathogen in the Neonatal Intensive Care Unit

被引：19

作者：

Carey, Alison J. ^{[1
]}

Long, Sarah S. ^{[2
]}

机构：

[1] St Christophers Hosp Children, Div Neonatol, Philadelphia, PA 19134 USA

[2] St Christophers Hosp Children, Div Infect Dis, Philadelphia, PA 19134 USA

来源：

CLINICS IN PERINATOLOGY | 2010年 / 37卷 / 03期

关键词：

Staphylococcus aureus; MRSA; MSSA; Neonates; NURSERY-ACQUIRED INFECTION; METHICILLIN-RESISTANT; BACTERIAL INTERFERENCE; RISK-FACTORS; EPIDEMIOLOGIC CHARACTERISTICS; NASAL CARRIAGE; ONSET SEPSIS; SCCMEC TYPE; VANCOMYCIN; COLONIZATION;

D O I：

10.1016/j.clp.2010.05.002

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Staphylococcus aureus is a continuously evolving and formidable pathogen that has been a problem for both healthy and sick neonates for decades. Much focus over the past 20 years has been on hospital-associated methicillinresistant S aureus (HA-MRSA); however, a global epidemic because of virulent community-associated MRSA (CA-MRSA) that has no "fitness cost" for carrying antibiotic-resistance genes has moved into neonatal intensive care units (NICUs). Recently, methicillin-susceptible S aureus has adopted some of the virulence factors of CA-MRSA and is an increasingly common cause of hospital-acquired infections in NICUs. This article reviews the changing epidemiology, clinical manifestations, and treatment of S aureus in neonates.

引用

页码：535 / +

页数：13

共 74 条

[1] Prevalence of methicillin-resistant Staphylococcus aureus nasal carriage in patients admitted to Driscoll Children's Hospital [J].

Alfaro, Carmen ;

Mascher-Denen, Marcella ;

Fergie, Jaime ;

Purcell, Kevin .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2006, 25 (05) :459-461

[2]

BOYCE JM, 1990, INFECT CONT HOSP EP, V11, P639

[3] Community-associated methicillin-resistant Staphylococcus aureus in hospital nursery and maternity units [J].

Bratu, S ;

Eramo, A ;

Kopec, R ;

Coughlin, E ;

Ghitan, M ;

Yost, R ;

Chapnick, EK ;

Landman, D ;

Quale, J .

EMERGING INFECTIOUS DISEASES, 2005, 11 (06) :808-813

[4] Emergence of community-associated methicillin-resistant Staphylococcus aureus at a Memphis, Tennessee children's hospital [J].

Buckingham, SC ;

McDougal, LK ;

Cathey, LD ;

Comeaux, K ;

Craig, AS ;

Fridkin, SK ;

Tenover, FC .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2004, 23 (07) :619-624

[5] The epidemiology of methicillin-susceptible and methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit, 2000-2007 [J].

Carey, A. J. ;

Duchon, J. ;

Della-Latta, P. ;

Saiman, L. .

JOURNAL OF PERINATOLOGY, 2010, 30 (02) :135-139

[6] Hospital-acquired infections in the NICU: Epidemiology for the new millennium [J].

Carey, Alison J. ;

Saiman, Lisa ;

Polin, Richard A. .

CLINICS IN PERINATOLOGY, 2008, 35 (01) :223-+

[7] Changes in the Molecular Epidemiological Characteristics of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit [J].

Carey, Alison J. ;

Della-Latta, Phyllis ;

Huard, Richard ;

Wu, Fann ;

Graham, Phillip L., III ;

Carp, Diane ;

Saiman, Lisa .

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2010, 31 (06) :613-619

[8] Inducible clindamycin resistance and molecular epidemiologic trends of pediatric community-acquired methicillin-resistant Staphylococcus aureus in Dallas, Texas [J].

Chavez-Bueno, S ;

Bozdogan, B ;

Katz, K ;

Bowlware, KL ;

Cushion, N ;

Cavuoti, D ;

Ahmad, N ;

McCracken, GH ;

Appelbaum, PC .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (06) :2283-2288

[9] Prevalence of methicillin-sensitive and methicillin-resistant Staphylococcus aureus in pregnant women [J].

Chen, Katherine T. ;

Huard, Richard C. ;

Della-Latta, Phyllis ;

Saiman, Lisa .

OBSTETRICS AND GYNECOLOGY, 2006, 108 (03) :482-487

[10]

COLBECK JC, 1949, CAN MED ASSOC J, V61, P557

← 1 2 3 4 5 6 7 8 →