Postbooster Antibodies from Humans as Source of Diphtheria Antitoxin

被引：5

作者：

Bermejo-Martin, Jesus F. ^{[1
]}

Avila-Alonso, Ana ^{[1
]}

Gonzalez-Rivera, Milagros ^{[2
]}

Tamayo, Eduardo ^{[1
]}

Maria Eiros, Jose ^{[1
]}

Almansa, Raquel ^{[1
]}

机构：

[1] Hosp Clin Univ Valladolid, Valladolid 47005, Spain

[2] Hosp Gen Univ Gregorio Maranon, Madrid, Spain

来源：

EMERGING INFECTIOUS DISEASES | 2016年 / 22卷 / 07期

关键词：

ACELLULAR PERTUSSIS-VACCINE; BOOSTER VACCINATION; TETANUS TOXOIDS; YOUNG-ADULTS; IMMUNOGENICITY; SAFETY; TRIAL;

D O I：

10.3201/eid2207.151670

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Diphtheria antitoxin for therapeutic use is in limited supply. A potential source might be affinity-purified antibodies originally derived from plasma of adults who received a booster dose of a vaccine containing diphtheria toxoid. These antibodies might be useful for treating even severe cases of diphtheria.

引用

页码：1265 / 1267

页数：3

共 15 条

[1] Evaluation of diphtheria convalescent patients to serve as donors for the production of anti-diphtheria immunoglobulin preparations [J].

Bissumbhar, B ;

Rakhmanova, AG ;

Berbers, GAM ;

Iakolev, A ;

Nosikova, E ;

Melnick, O ;

Ovtcharenko, E ;

Rümke, HC ;

Ruitenberg, EJ .

VACCINE, 2004, 22 (15-16) :1886-1891

[2] Immunogenicity and safety of a tetanus toxoid, reduced diphtheria toxoid and three-component acellular pertussis vaccine in adults 19-64 years of age [J].

Blatter, Mark ;

Friedland, Leonard R. ;

Weston, Wayde M. ;

Li, Ping ;

Howe, Barbara .

VACCINE, 2009, 27 (05) :765-772

[3] Access to diphtheria antitoxin for therapy and diagnostics [J].

Both, L. ;

White, J. ;

Mandal, S. ;

Efstratiou, A. .

EUROSURVEILLANCE, 2014, 19 (24) :19-24

[4]

Centers for Disease Control and Prevention, USE OF DIPHTHERIA AN

[5] Affinity-puritied human immunoglobulin G that binds a lacto-N-neotetraose-dependent lipooligosaccharide structure is bactericidal for serogroup B Neisseria meningitidis [J].

Estabrook, Michele M. ;

Jarvis, Gary A. ;

Griffiss, J. McLeod .

INFECTION AND IMMUNITY, 2007, 75 (02) :1025-1033

[6]

European Centre for Disease Prevention and Control, RAP RISK ASS CAS DIP

[7] Tolerability and antibody response in adolescents and adults revaccinated with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine adsorbed (Tdap) 4-5 years after a previous dose [J].

Halperin, Scott A. ;

McNeil, Shelly ;

Langley, Joanne ;

Blatter, Mark ;

Dionne, Marc ;

Embree, Joanne ;

Johnson, Roehl ;

Latiolais, Thomas ;

Meekison, William ;

Noya, Francisco ;

Senders, Shelly ;

Zickler, Paul ;

Johnson, David R. .

VACCINE, 2011, 29 (46) :8459-8465

[8] Immunogenicity and Safety after Booster Vaccination of Diphtheria, Tetanus, and Acellular Pertussis in Young Adults: an Open Randomized Controlled Trial in Japan [J].

Hara, Megumi ;

Okada, Kenji ;

Yamaguchi, Yuko ;

Uno, Shingo ;

Otsuka, Yasuko ;

Shimanoe, Chisato ;

Nanri, Hinako ;

Horita, Mikako ;

Ozaki, Iwata ;

Nishida, Yuichiro ;

Tanaka, Keitaro .

CLINICAL AND VACCINE IMMUNOLOGY, 2013, 20 (12) :1799-1804

[9] Booster vaccination in the elderly:: Their success depends on the vaccine type applied earlier in life as well as on pre-vaccination antibody titers [J].

Kaml, Maria ;

Weiskirchner, Ilka ;

Keller, Michael ;

Luft, Thomas ;

Hoster, Eva ;

Hasford, Joerg ;

Young, Linda ;

Bartlett, Bill ;

Neuner, Christoph ;

Fischer, Karl-Heinz ;

Neuman, Ber ;

Wuerzner, Reinhard ;

Grubeck-Loebenstein, Beatrix .

VACCINE, 2006, 24 (47-48) :6808-6811

[10] Decennial Administration of a Reduced Antigen Content Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine in Young Adults [J].

Mertsola, Jussi ;

Van Der Meeren, Olivier ;

He, Qiushui ;

Linko-Parvinen, Anna ;

Ramakrishnan, Gunasekaran ;

Mannermaa, Leni ;

Soila, Maaria ;

Pulkkinen, Markku ;

Jacquet, Jeanne-Marie .

CLINICAL INFECTIOUS DISEASES, 2010, 51 (06) :656-662

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