2,3-Dichloro-1,4-Naphthoquinone in Organic Synthesis: Recent Advances

被引:4
作者
Forezi, Luana da S. M. [1 ]
Cardoso, Mariana F. C. [1 ]
Costa, Dora C. S. [1 ]
da Silva, Fernando de C. [1 ]
Ferreira, Vitor F. [1 ]
机构
[1] Univ Fed Fluminense, Inst Quim, Dept Quim Organ, Campus Valonguinho, BR-24020150 Niteroi, RJ, Brazil
关键词
Quinones; synthetic applications; biological activity; heterocycles; cyclization reactions; nucleophilic substitutions; napthoquinone; SULFUR-CONTAINING HETERO-1,4-NAPHTHOQUINONES; 1,4-NAPHTHOQUINONE DERIVATIVES; BIOLOGICAL EVALUATION; TRYPANOSOMA-CRUZI; IN-VITRO; EXTENDED TETRATHIAFULVALENE; TRYPANOCIDAL ACTIVITY; POTENT ANTIFUNGAL; NAPHTHOQUINONES; ANTIBACTERIAL;
D O I
10.2174/1570193X14666170518125507
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
2,3-Dichloro-1,4-naphthoquinone is a special naphthoquinone with four electrophilic sites, useful for applications in organic synthesis and preparation of a diverse new compounds, such as 2,3-substituted derivatives and heterocycles, including those with the core naphthoquinone structure fused. It has also been used for the preparation of compounds for evaluation against several biological targets. This review will describe the most recent applications of 2,3-dichloro-1,4-naphthoquinone in organic synthesis.
引用
收藏
页码:375 / 390
页数:16
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