Melanin and blood concentration in human skin studied by multiple regression analysis: experiments

被引：40

作者：

Shimada, M

Yamada, Y

Itoh, M

Yatagai, T

机构：

[1] Tokyo Inst Psychiat, Dept Integrated Neurosci, Setagaya Ku, Tokyo 1568585, Japan

[2] Univ Electrocommun, Dept Mech Engn & Intelligent Syst, Tokyo 1828585, Japan

[3] Natl Inst Adv Ind Sci & Technol, Inst Human Sci & Biomed Engn, Tsukuba, Ibaraki 3058564, Japan

[4] Univ Tsukuba, Inst Appl Phys, Tsukuba, Ibaraki 3058573, Japan

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 2001年 / 46卷 / 09期

关键词：

D O I：

10.1088/0031-9155/46/9/308

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Knowledge of the mechanism of human skin colour and measurement of melanin and blood concentration in human skin are needed in the medical and cosmetic fields. The absorbance spectrum from reflectance at the visible wavelength of human skin increases under several conditions such as a sunburn or scalding. The change of the absorbance spectrum from reflectance including the scattering effect does not correspond to the molar absorption spectrum of melanin and blood. The modified Beer-Lambert law is applied to the change in the absorbance spectrum from reflectance of human skin as the change in melanin and blood is assumed to be small. The concentration of melanin and blood was estimated from the absorbance spectrum reflectance of human skin using multiple regression analysis. Estimated concentrations were compared with the measured one in a phantom experiment and this method was applied to in vivo skin.

引用

页码：2385 / 2395

页数：11