Antioxidant activity of the methanolic extract of the newly generated vegetable, baemuchae (xBrassicoraphanus)

被引：3
|
作者：
Mok, So-Youn [2 ]
Choi, Mi Jin [1 ]
Kim, Jongkee [2 ]
Cho, Eun Ju [1 ]
Lee, Sanghyun [2 ]
机构：
[1] Pusan Natl Univ, Dept Food Sci & Nutr, Pusan 609735, South Korea
[2] Chung Ang Univ, Dept Integrat Plant Sci, Anseong 456756, South Korea
来源：
FOOD AND CHEMICAL TOXICOLOGY | 2012年 / 50卷 / 3-4期
关键词：
Antioxidant activity; Baemuchae (xBrassicoraphanus); Ferulic acid; Radical scavenging effect; OXIDATIVE STRESS; FERULIC ACID; NITRIC-OXIDE; PHENOLIC-ACIDS; FREE-RADICALS; PEROXYNITRITE; DAMAGE; L;
D O I：
10.1016/j.fct.2012.01.006
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
We investigated the radical scavenging activity and protective effects of the methanol extract (ME) and ferulic acid (FA) from baemuchae (xBrassicoraphanus) against oxidative stress in vitro and on a cellular system using LLC-PK1 renal epithelial cells. In vitro, ME and FA showed dose-dependent radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl and hydroxyl radicals. LLC-PK1 cells displayed decreased viability in response to nitric oxide-induced oxidative stress. However. ME and FA significantly increased LLC-PK1 cell viability in a dose-dependent manner. Based on HPLC/UV analysis, the FA content was higher in the shoot of baemuchae than in the root. The results of the present study suggest that baemuchae may be a promising source of antioxidants against oxidative stress induced by free radicals. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：848 / 853
页数：6
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