Tris(2,4,6-trimethoxyphenyl)methyl carbenium ion for charge derivatization of amines and amino acids

被引：19

作者：

Denekamp, Chagit ^{[1
]}

Lacour, Jerome ^{[2
]}

Laleu, Benoit ^{[2
]}

Rabkin, Emilia ^{[1
]}

机构：

[1] Technion Israel Inst Technol, Dept Chem, IL-32000 Haifa, Israel

[2] Univ Geneva, Dept Chim Organ, CH-1211 Geneva 4, Switzerland

来源：

JOURNAL OF MASS SPECTROMETRY | 2008年 / 43卷 / 05期

关键词：

tris(2,4,6-trimethoxyphenyl)methyl carbenium ion; MALDI-TOF; matrix; amines analysis; amino acids;

D O I：

10.1002/jms.1360

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Primary and secondary alkyl amines substitute readily one of the para-methoxy substituents of tris(2,4,6-trimethoxyphenyl)methyl carbenium ion. With this rapid process, the preparation of permanently charged positive derivatives of amines, amino acids and small C-protected peptides is achieved. This is utilized here to facilitate the matrix assisted laser desorption ionization-time-of-flight (MALDI-TOF) analysis of these compounds. Copyright (C) 2007 John Wiley & Sons, Ltd.

引用

页码：623 / 627

页数：5

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