Accuracy of stool antigen test in posteradication assessment of Helicobacter pylori infection

被引:18
作者
Manes, G
Balzano, A
Iaquinto, G
Ricci, C
Piccirillo, MM
Giardullo, N
Todisco, A
Lioniello, M
Vaira, D
机构
[1] Osped Antonio Cardarelli, Dept Gastroenterol, I-80129 Naples, Italy
[2] Osped Antonio Cardarelli, Cent Lab, I-80129 Naples, Italy
[3] San G Moscati Hosp, Dept Gastroenterol, Avellino, Italy
[4] San G Moscati Hosp, Cent Lab, Avellino, Italy
[5] Univ Bologna, Med Clin, I-40126 Bologna, Italy
关键词
Helicobacter pylori; stool; antigen; C-13]urea breath test; treatment outcome;
D O I
10.1023/A:1012319718848
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Our aim was to evaluate the accuracy of HpSA test in the diagnosis of Helicobacter pylori infection after the end of eradication therapy. In all 106 H. pylori-positive patients (55 men and 51 women, mean age 51 years, range 19-82) were treated with a course of eradicating regimen. [C-13]Urea breath test (UBT) and HpSA were performed four weeks after stopping the treatment. The diagnostic accuracy of HpSA was evaluated in comparison with the results of [13C] UBT. In 90 patients (85%) H. pylori was eradicated according to [C-13]urea breath test. After eradication, sensitivity of HpSA was 87.5%, specificity 95.5%, positive predictive value 77.8%, negative predictive value 97.7%, and diagnostic accuracy 94.3%. HpSA is a valuable test in the posteradication assessment of H. pylori infection.
引用
收藏
页码:2440 / 2444
页数:5
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