Where the adhesive and fibrinolytic systems meet:: Urokinase-type plasminogen activator (uPA) is a ligand for integrin αMβ2 (CD11b/18).

被引：0
|
作者：
Pluskota, E [1 ]
Soloviev, DA [1 ]
Plow, EF [1 ]
机构：
[1] Cleveland Clin Fdn, Cleveland, OH 44195 USA
来源：
BLOOD | 2001年 / 98卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
2925
引用
收藏
页码：700A / 700A
页数：1
相关论文
共 47 条
  • [1] Ligand-engaged urokinase-type plasminogen activator receptor and activation of the CD11b/CD18 integrin inhibit late events of HIV expression in monocytic cells
    Alfano, Massimo
    Mariani, Samanta A.
    Elia, Chiara
    Pardi, Ruggero
    Blasi, Francesco
    Poli, Guido
    BLOOD, 2009, 113 (08) : 1699 - 1709
  • [2] Elevated expression of CD87 and its ligand urokinase-type plasminogen activator (uPA) in lipodermatosclerosis
    Herouy, Y
    Stetter, C
    May, AE
    Schopf, E
    Vanscheidt, W
    Norgauer, J
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1998, 110 (04) : 599 - 599
  • [3] Urokinase-type plasminogen activator receptor reversibly dissociates from complement receptor type 3 (alpha(M)beta(2')CD11b/CD18) during neutrophil polarization
    Kindzelskii, AL
    Laska, ZO
    Todd, RF
    Petty, HR
    JOURNAL OF IMMUNOLOGY, 1996, 156 (01): : 297 - 309
  • [4] Down-regulation of integrin αMβ2 ligand-binding function by the urokinase-type plasminogen activator receptor
    Tang, Man-Li
    Kong, Le-Sheng
    Law, S. K. Alex
    Tan, Suet-Mien
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2006, 348 (03) : 1184 - 1193
  • [5] HEPARIN IS AN ADHESIVE LIGAND FOR THE LEUKOCYTE INTEGRIN MAC-1 (CD11B/CD18)
    DIAMOND, MS
    ALON, R
    PARKOS, CA
    QUINN, MT
    SPRINGER, TA
    JOURNAL OF CELL BIOLOGY, 1995, 130 (06): : 1473 - 1482
  • [6] Platelet glycoprotein lbα is an adhesive ligand for the leukocyte integrin Mac-1 (CD11b/CD18)
    Simon, DI
    Xu, H
    Ballantyne, CM
    Berndt, MC
    Lopez, JA
    CIRCULATION, 1999, 100 (18) : 333 - 333
  • [7] Analysis of the integrin αMβ2 (CD11b/CD18) ligand binding promiscuity using inter-integrin chimera.
    Yakubenko, V
    Lishko, V
    Lam, S
    Ugarova, T
    BLOOD, 2002, 100 (11) : 459A - 459A
  • [8] Urokinase-type plasminogen activator receptor induces conformational changes in the integrin αMβ2 headpiece and reorientation of its transmembrane domains
    Tang, Man-Li
    Vararattanavech, Ardcharaporn
    Tan, Suet-Mien
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (37) : 25392 - 25403
  • [9] Quantitative assessment of interaction of urokinase-type plasminogen activator and its receptor (CD87) by use of a solid-phase uPA-ligand binding assay
    Goretzki, L
    Bognacki, J
    Koppitz, M
    Rettenberger, P
    Magdolen, V
    Creutzburg, S
    Hammelburger, J
    Weidle, UH
    Wilhelm, O
    Kessler, H
    Graeff, H
    Schmitt, M
    FIBRINOLYSIS & PROTEOLYSIS, 1997, 11 (01): : 11 - 19
  • [10] Ligand Recognition Specificity of Leukocyte Integrin αMβ2 (Mac-1, CD11b/CD18) and Its Functional Consequences
    Podolnikova, Nataly P.
    Podolnikov, Andriy V.
    Haas, Thomas A.
    Lishko, Valeryi K.
    Ugarova, Tatiana P.
    BIOCHEMISTRY, 2015, 54 (06) : 1408 - 1420
12345