The Future of Adult Cardiac Assist Devices: Novel Systems and Mechanical Circulatory Support Strategies

被引：34
作者：
Bartoli, Carlo R. [1 ]
Dowling, Robert D. [2 ]
机构：
[1] Univ Louisville, Dept Physiol & Biophys, Sch Med, MD PhD Program, Louisville, KY 40292 USA
[2] Univ Louisville, Dept Surg, Louisville, KY 40292 USA
来源：
CARDIOLOGY CLINICS | 2011年 / 29卷 / 04期
关键词：
Heart failure; Left ventricular assist device (LVAD); Right ventricular assist device (RVAD); Total artificial heart (TAH); Pulsatile flow; Continuous flow; Full support; Partial support; Mechanical circulatory support; INTRAAORTIC BALLOON PUMP; TOTAL ARTIFICIAL-HEART; SUBCUTANEOUS COUNTERPULSATION DEVICE; IN-VIVO EVALUATION; MAGNETICALLY LEVITATED ROTOR; PARTIAL VENTRICULAR SUPPORT; ACUTE HEMODYNAMIC EFFICACY; ROTARY BLOOD PUMP; MYOCARDIAL RECOVERY; INITIAL-EXPERIENCE;
D O I：
10.1016/j.ccl.2011.08.013
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The recent, widespread success of mechanical circulatory support has prompted the development of numerous implantable devices to treat advanced heart failure. It is important to raise awareness of novel device systems, the mechanisms by which they function, and implications for patient management. This article discusses devices that are being developed or are in clinical trials. Devices are categorized as standard full support, less-invasive full support, partial support: rotary pumps, partial support: counterpulsation devices, right ventricular assist device, and total artificial heart. Implantation strategy, mechanism of action, durability, efficacy, hemocompatibility, and human factors are considered. The feasibility of novel strategies for unloading the failing heart is examined.
引用
收藏
页码：559 / +
页数：26
相关论文
共 120 条
[1]   Rotary blood pump flow spontaneously increases during exercise under constant pump speed: Results of a chronic study [J].
Akimoto, T ;
Yamazaki, K ;
Litwak, P ;
Litwak, KN ;
Tagusari, O ;
Mori, T ;
Antaki, JF ;
Kameneva, MV ;
Watach, MJ ;
Umezu, M ;
Tomioka, J ;
Kormos, RL ;
Koyanagi, H ;
Griffith, BP .
ARTIFICIAL ORGANS, 1999, 23 (08) :797-801
[2]   NHLBI's Program for VAD Therapy for Moderately Advanced Heart Failure: The REVIVE-IT Pilot Trial [J].
Baldwin, J. Timothy ;
Mann, Douglas L. .
JOURNAL OF CARDIAC FAILURE, 2010, 16 (11) :855-858
[3]   The national heart, lung, and blood institute pediatric circulatory support program [J].
Baldwin, JT ;
Borovetz, HS ;
Duncan, BW ;
Gartner, MJ ;
Jarvik, RK ;
Weiss, WJ ;
Hoke, TR .
CIRCULATION, 2006, 113 (01) :147-155
[4]   Hemodynamic Responses to Continuous versus Pulsatile Mechanical Unloading of the Failing Left Ventricle [J].
Bartoli, Carlo R. ;
Giridharan, Guruprasad A. ;
Litwak, Kenneth N. ;
Sobieski, Michael ;
Prabhu, Sumanth D. ;
Slaughter, Mark S. ;
Koenig, Steven C. .
ASAIO JOURNAL, 2010, 56 (05) :410-416
[5]   A Novel Subcutaneous Counterpulsation Device: Acute Hemodynamic Efficacy During Pharmacologically Induced Hypertension, Hypotension, and Heart Failure [J].
Bartoli, Carlo R. ;
Wilson, Gregory C. ;
Giridharan, Guruprasad A. ;
Slaughter, Mark S. ;
Sherwood, Leslie C. ;
Spence, Paul A. ;
Prabhu, Sumanth D. ;
Koenig, Steven C. .
ARTIFICIAL ORGANS, 2010, 34 (07) :537-545
[6]  
BARTOLI CR, 2010, TOTAL ARTIFICIAL HEA
[7]   The role of bridge to transplantation: should LVAD patients be transplanted? [J].
Birks, EJ ;
Yacoub, MH ;
Banner, NR ;
Khaghani, A .
CURRENT OPINION IN CARDIOLOGY, 2004, 19 (02) :148-153
[8]   Left ventricular assist device and drug therapy for the reversal of heart failure [J].
Birks, Emma J. ;
Tansley, Patrick D. ;
Hardy, James ;
George, Robert S. ;
Bowles, Christopher T. ;
Burke, Margaret ;
Banner, Nicholas R. ;
Khaghani, Asghar ;
Yacoub, Magdi H. .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (18) :1873-1884
[9]   Molecular Changes Occurring During Reverse Remodelling Following Left Ventricular Assist Device Support [J].
Birks, Emma J. ;
George, Robert S. .
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 2010, 3 (06) :635-642
[10]  
Boening Andreas, 2004, Interact Cardiovasc Thorac Surg, V3, P495, DOI 10.1016/j.icvts.2004.04.007
12345678910