Catalytic Decarboxylative Fluorosulfonylation Enabled by Energy-Transfer-Mediated Photocatalysis

被引：57

作者：

Chen, Zhi-Da ^{[1
]}

Zhou, Xiang ^{[1
]}

Yi, Ji-Tao ^{[1
]}

Diao, Hong-Juan ^{[2
]}

Chen, Qi-Long ^{[1
]}

Lu, Gui ^{[1
]}

Weng, Jiang ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab Chiral Mol & Drug Discover, Guangzhou 510006, Peoples R China

[2] Zhejiang Univ Technol, Coll Biotechnol & Bioengn, Key Lab Bioorgan Synth Zhejiang Prov, Hangzhou 310014, Peoples R China

来源：

ORGANIC LETTERS | 2022年 / 24卷 / 13期

关键词：

SULFONYL FLUORIDES; THIOSULFONATES; DISULFIDES; PHOTOREDOX; OXIDATION; SUFEX;

D O I：

10.1021/acs.orglett.2c00459

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sulfonyl fluorides are useful building blocks in a wide array of fields. Herein, we report a catalytic decarboxylative fluorosulfonylation approach for converting abundant aliphatic carboxylic acids to the corresponding sulfonyl fluorides. This transformation is enabled by simple preactivation as aldoxime esters and energy-transfer-mediated photocatalysis. This operationally simple method proceeds with high functional-group tolerance under mild and redox-neutral conditions.

引用

页码：2474 / 2478

页数：5

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