Pulse-Driven Magnetoimpedance Sensor Detection of Cardiac Magnetic Activity

被引:21
作者
Nakayama, Shinsuke [1 ]
Sawamura, Kenta [1 ]
Mohri, Kaneo [2 ]
Uchiyama, Tsuyoshi [2 ]
机构
[1] Nagoya Univ, Dept Cell Physiol, Grad Sch Med, Nagoya, Aichi 4648601, Japan
[2] Nagoya Univ, Dept Elect, Grad Sch Engn, Nagoya, Aichi 4648601, Japan
基金
日本科学技术振兴机构; 日本学术振兴会;
关键词
PLURIPOTENT STEM-CELLS; SEGMENT; WIRE;
D O I
10.1371/journal.pone.0025834
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
This study sought to establish a convenient method for detecting biomagnetic activity in the heart. Electrical activity of the heart simultaneously induces a magnetic field. Detection of this magnetic activity will enable non-contact, noninvasive evaluation to be made. We improved the sensitivity of a pulse-driven magnetoimpedance (PMI) sensor, which is used as an electric compass in mobile phones and as a motion sensor of the operation handle in computer games, toward a pico-Tesla (pT) level, and measured magnetic fields on the surface of the thoracic wall in humans. The changes in magnetic field detected by this sensor synchronized with the electric activity of the electrocardiogram (ECG). The shape of the magnetic wave was largely altered by shifting the sensor position within 20 mm in parallel and/or perpendicular to the thoracic wall. The magnetic activity was maximal in the 4th intercostals near the center of the sterna. Furthermore, averaging the magnetic activity at 15 mm in the distance between the thoracic wall and the sensor demonstrated magnetic waves mimicking the P wave and QRS complex. The present study shows the application of PMI sensor in detecting cardiac magnetic activity in several healthy subjects, and suggests future applications of this technology in medicine and biology.
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页数:6
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