Association between telomere length and cognitive ability in a community-based sample

被引：11

作者：

Kaja, Rishika ^{[1
]}

Reyes, Stephanie M. ^{[1
]}

Rossetti, Heidi C. ^{[1
]}

Brown, E. Sherwood ^{[1
]}

机构：

[1] Univ Texas Southwestern Med Ctr Dallas, Dept Psychiat, 5323 Harry Hines Blvd, Dallas, TX 75390 USA

来源：

NEUROBIOLOGY OF AGING | 2019年 / 75卷

基金：

美国国家卫生研究院;

关键词：

Telomere; Cognitive ability; Cognitive aging; Cellular biomarker; Community-based sample; MORTALITY; HEALTH;

D O I：

10.1016/j.neurobiolaging.2018.11.006

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Prior research suggests that telomere length is a biomarker of cognitive aging; however, literature has demonstrated conflicting findings to date. The present study uses data from the Dallas Heart Study, N = 2606, to assess the association between telomere length and cognitive ability on the Montreal Cognitive Assessment. The data do not support a relationship between telomere length and general cognitive functioning, (beta = 0.016, SE = 0.31, p = 0.407). The data further replicate the negative findings within current literature. (C) 2018 Elsevier Inc. All rights reserved.

引用

页码：51 / 53

页数：3

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