Effects of denaturing acid on the self-association behaviour of poly(ethylene glycol)-block-poly(γ-benzyl L-glutamate)-graft-poly(ethylene glycol) copolymer in ethanol

被引：0
作者：
Zhu, Guo-Quan [1 ]
Gao, Qiao-Chun [1 ]
Wang, Fa-Gang [1 ]
Li, Guo-Chang [1 ]
Wang, Ping [1 ]
机构：
[1] Shandong Univ Technol, Sch Mat Sci & Engn, Zibo 255049, Peoples R China
来源：
CHEMICAL PAPERS | 2011年 / 65卷 / 04期
关键词：
copolymer; denaturing acid; PEG-b-PBLG-g-PEG; self-association behaviour; mixed system; POLY(GAMMA-BENZYL L-GLUTAMATE) HOMOPOLYMER; POLYPEPTIDE BLOCK-COPOLYMER; GRAFT COPOLYMER; POLYMERIC MICELLES; HYDROPHOBIC PART; HYDROPHILIC PART; SIDE-CHAINS; OXIDE); NANOPARTICLES; TRANSITION;
D O I：
10.2478/s11696-011-0021-6
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Poly(ethylene glycol)-block-poly(gamma-benzyl L-glutamate)-graft-poly(ethylene glycol) (PEG-b-PBLG-g-PEG) copolymer was synthesised by the ester exchange reaction of PEG-block-PBLG copolymer with mPEG. The self-association behaviour of PEG-b-PBLG-g-PEG in mixtures of ethanol, chloroform, and trifluoroacetic acid as denaturing acid was investigated by transmission electron microscopy, nuclear magnetic resonance spectroscopy, FT-IR spectroscopy, dynamic light scattering, and viscometry. It was revealed that the increase in denaturing acid content in the mixed system not only promoted the critical micelle concentration but also changed the morphology of the polymeric micelles from elliptical to spherical. (C) 2011 Institute of Chemistry, Slovak Academy of Sciences
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页码：477 / 482
页数：6
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