SARS-CoV-2 AY.4.2 variant circulating in Italy: Genomic preliminary insight

被引：11

作者：

Angeletti, Silvia ^{[1
]}

Giovanetti, Marta ^{[2
]}

Fogolari, Marta ^{[1
]}

Cella, Eleonora ^{[3
]}

De Florio, Lucia ^{[1
]}

Lintas, Carla ^{[1
]}

Veralli, Roberta ^{[1
]}

Francesconi, Maria ^{[1
]}

Caccuri, Francesca ^{[4
]}

De Cesaris, Marina ^{[1
]}

De Flora, Cecilia ^{[1
]}

Ceccarelli, Giancarlo ^{[5
]}

Spoto, Silvia ^{[6
]}

Caruso, Arnaldo ^{[4
]}

Pascarella, Stefano ^{[7
]}

Riva, Elisabetta ^{[8
]}

Ciccozzi, Massimo ^{[9
]}

机构：

[1] Univ Campus Biomed Rome, Unit Clin Lab Sci, Rome, Italy

[2] Fundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Flavivirus, Av Brasil 4365, BR-21040360 Rio De Janeiro, Brazil

[3] Univ Cent Florida, Burnett Sch Biomed Sci, Orlando, FL 32816 USA

[4] Univ Brescia, Dept Mol & Translat Med, Sect Microbiol, Brescia, Italy

[5] Univ Sapienza, Dept Publ Hlth & Infect Dis, Policlin Umberto I, Rome, Italy

[6] Univ Campus Biomed Rome, Diagnost & Therapeut Med Div, Rome, Italy

[7] Univ Roma La Sapienza, Dept Biochem Sci A Rossi Fanelli, Rome, Italy

[8] Univ Campus Biomed Rome, Unit Virol, Rome, Italy

[9] Univ Campus Biomed Rome, Unit Med Stat & Mol Epidemiol, Rome, Italy

来源：

JOURNAL OF MEDICAL VIROLOGY | 2022年 / 94卷 / 04期

关键词：

AY; 4; 2; variant; genomic surveillance; Italy; SARS-CoV-2;

D O I：

10.1002/jmv.27451

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The appearance of emerging variants of SARS-CoV-2 carrying mutations into the spike protein has recently raised concern with respect to tracking their transmission and mitigating the impact in the evolving pandemic across countries. AY.4.2, a recently detected Delta variant sublineage, is considered a new variant under investigation (VUI) as it carries specific genetic signatures present in the spike protein, called Y145H and A222V. Here, using genomic epidemiology, we provide the first preliminary insight regarding the circulation of this emerging VUI in Italy.

引用

页码：1689 / 1692

页数：4

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