ELANE MUTATION C233TER PREDISPOSES PATIENTS WITH SEVERE CONGENITAL NEUTROPENIA TO ACUTE MYELOID LEUKEMIA

被引:0
作者
Dale, D. [1 ]
Bolyard, A. A. [1 ]
Kelley, M. [1 ]
Makaryan, V. [1 ]
Boxer, L. [2 ]
Bonilla, M. A. [3 ]
Cavieres, M. [4 ]
Tan, P. [5 ]
Firkin, F. [6 ]
机构
[1] Univ Washington, Med, Seattle, WA 98195 USA
[2] Univ Michigan, Pediat Hematol Oncol, Ann Arbor, MI 48109 USA
[3] St Josephs Childrens Hosp, Pediat Hematol Oncol, Paterson, NJ USA
[4] Hosp Ninos Luis Calvo Mackenna, Hematol, Santiago, Chile
[5] Hollywood Med Ctr, Hematol, Nedlands, WA, Australia
[6] St Vincents Hosp, Med, Fitzroy, Vic, Australia
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
PB1661
引用
收藏
页码:679 / 679
页数:1
相关论文
共 50 条
[41]   CRISPR-Cas9-Mediated ELANE Mutation Correction in Hematopoietic Stem and Progenitor Cells to Treat Severe Congenital Neutropenia [J].
Ngoc Tung Tran ;
Graf, Robin ;
Wulf-Goldenberg, Annika ;
Stecklum, Maria ;
Strauss, Gabriele ;
Kuehn, Ralf ;
Kocks, Christine ;
Rajewsky, Klaus ;
Van Trung Chu .
MOLECULAR THERAPY, 2020, 28 (12) :2621-2634
[42]   Comparison of abnormalities in myeloid cells between patients with cyclic neutropenia and severe congenital neutropenia. [J].
Kawaguchi, H ;
Kobayashi, M ;
Nakamura, K ;
Sato, T ;
Kojima, S ;
Katoh, O ;
Ueda, K .
BLOOD, 2002, 100 (11) :243A-243A
[43]   Absence of Neutropenia in Patients With Early Exon Nonsense Mutations in ELANE: Clinical Evidence to Support Gene Therapy Approaches for Severe Congenital Neutropenia [J].
Joos, Margret ;
Chang, Timothy H. ;
Shimamura, Akiko ;
Newburger, Peter E. .
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2024, 46 (06) :e463-e465
[44]   Clinical Characteristics and Treatment Response of a Novel ELANE Gene Mutation (c.295_303del) in Congenital Neutropenia [J].
Ning, Junjie .
MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES, 2024, 16 (01)
[46]   Defective proliferation of primitive myeloid progenitor cells in patients with severe congenital neutropenia [J].
Konishi, N ;
Kobayashi, M ;
Miyagawa, S ;
Sato, T ;
Katoh, O ;
Ueda, K .
BLOOD, 1999, 94 (12) :4077-4083
[47]   Nucleophosmin gene mutation in acute myeloid leukemia patients [J].
Khorshied, Mervat M. ;
Said, Wael A. ;
Shaaban, Hebat A. .
SAUDI MEDICAL JOURNAL, 2010, 31 (05) :582-584
[48]   Small Molecule Inhibitor of Neutrophil Elastase Normalizes Myeloid Differentiation and Improves Impaired Cell Survival Triggered by Elastase Mutations In Patients with Severe Congenital Neutropenia and Acute Myeloid Leukemia [J].
Aprikyan, Andrew A. ;
Makaryan, Vahagn ;
Totrov, Maxim ;
Abagyan, Ruben ;
Dale, David C. .
BLOOD, 2010, 116 (21) :173-174
[49]   SIGNIFICANCE OF FEBRILE NEUTROPENIA RISK SCORE IN PATIENTS WITH ACUTE MYELOID LEUKEMIA [J].
Vidovic, A. ;
Virijevic, M. ;
Djunic, I. ;
Tomin, D. ;
Vukovic, N. Suvajdzic ;
Colovic, N. ;
Mitrovic, M. ;
Arsenijevic, V. Arsic ;
Pavlovic, S. ;
Mihaljevic, B. .
HAEMATOLOGICA, 2014, 99 :574-575
[50]   Acquired substitution mutation in G-CSF receptor underlying evolution of severe congenital neutropenia to acute myelogenous leukemia. [J].
Aprikyan, AAG ;
Rodger, ER ;
Jeha, S ;
Boxer, LA ;
Dale, DC .
BLOOD, 2000, 96 (11) :185B-185B