Impact of FVIII source in the Bethesda-Nijmegen inhibitor test result. Difference between FVIII/VWF complex concentrates and concentrates of isolated FVIII

被引：0

作者：

Isabel Bravo, Maria ^{[1
]}

Maria Ortiz, Ana ^{[1
]}

Costa, Montserrat ^{[1
]}

Grancha, Salvador ^{[1
]}

Ignacio Jorquera, Juan ^{[1
]}

机构：

[1] Inst Grifols SA, Barcelona, Spain

来源：

HAEMOPHILIA | 2016年 / 22卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：65 / 65

页数：1

共 12 条

[1] Inhibitor neutralizing capacity of FVIII therapeutic concentrates depends on VWF: Natural FVIII/VWF complex versus isolated FVIII. Study of eleven products
Isabel Bravo, Maria
Maria Ortiz, Ana
Costa, Montserrat
Grancha, Salvador
Ignacio Jorquera, Juan
HAEMOPHILIA, 2016, 22 : 64 - 64
[2] Neutralizing capacity of inhibitors on FVIII is lower for natural FVIII/VWF complex than for isolated FVIII: in vitro comparative study in eleven different therapeutic FVIII concentrates
Bravo, M. I.
Ortiz, A. M.
Costa, M.
Grancha, S.
Jorquera, J. I.
HAEMOPHILIA, 2016, 22 (04) : E341 - E344
[3] Native plasma-derived FVIII/VWF complex has lower sensitivity to FVIII inhibitors than the combination of isolated FVIII and VWF proteins. Impact on Bethesda assay titration of FVIII inhibitors
Bravo, M. I.
Da Rocha-Souto, B.
Grancha, S.
Jorquera, J. I.
HAEMOPHILIA, 2014, 20 (06) : 905 - 911
[4] Beneficial effect of VWF in FVIII recovery of different FVIII concentrates in a mouse model of severe hemophilia with high inhibitor titers
Bravo, M., I
Costa, M.
Grancha, S.
Jorquera, J., I
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2015, 13 : 826 - 827
[5] Highly discrepant inhibitor titres in the Bethesda assay as a function of FVIII source: plasma vs. isolated FVIII
Bravo, M., I
Da Rocha-Souto, B.
Grancha, S.
Jorquera, J., I
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2014, 12 : 36 - 36
[6] EFFECT OF PLATELETS ON THE INVITRO RESPONSE TO PROTHROMBIN COMPLEX CONCENTRATES IN FVIII INHIBITOR PLASMA
CASTALDI, PA
SMITH, IL
PATHOLOGY, 1980, 12 (01) : 111 - 118
[7] The role of natural VWF/FVIII complex concentrates in contemporary haemophilia care: a guideline for the next decade
Mannucci, P. M.
HAEMOPHILIA, 2012, 18 : 2 - 7
[8] Prednisone and low-dose activated prothrombin complex concentrates for FVIII inhibitor in nonhaemophilic patients
Ji, LX
Yang, RC
Yang, DG
Chen, ZK
Xing, SH
Tian, MG
Sun, Y
HAEMOPHILIA, 1998, 4 (05) : 721 - 724
[9] PdFVIII/VWF concentrates show significantly lower titres in the Bethesda assay than recombinant FVIII products; a kinetic in vitro inhibition study
Isabel Bravo, Maria
Darocha-Souto, Bibiana
Grancha, Salvador
Ignacio Jorquera, Juan
HAEMOPHILIA, 2014, 20 : 44 - 44
[10] Characterization of factor VIII-von Willebrand Factor (FVIII-VWF)-complex concentrates under shear stress
Siekmann, J
Schwarz, HP
Turecek, L
34TH HEMOPHILIA SYMPOSIUM, 2005, : 361 - 367

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