Subarachnoid haemorrhage in pregnancy after in vitro fertilisation with egg donation: a case report and review of the literature

被引:0
作者
Hughes, Noemi J. [1 ]
Choudhury, Saeed M. S. R. [2 ]
Liyanage, Sidath H. [3 ]
Hussain, Munawar [1 ]
机构
[1] Southend Univ Hosp NHS Fdn Trust, Dept Obstet & Gynaecol, Southend On Sea SS0 0RY, England
[2] Southend Univ Hosp NHS Fdn Trust, Dept Med, Southend On Sea, England
[3] Southend Univ Hosp NHS Fdn Trust, Dept Radiol, Southend On Sea, England
来源
THERAPEUTIC ADVANCES IN REPRODUCTIVE HEALTH | 2021年 / 15卷
关键词
aneurysm; CVA; fertility; IVF; pregnancy; SAH; thrombosis; EMBRYO-TRANSFER; THROMBOPHILIA; ASSOCIATION; RISK;
D O I
10.1177/26334941211023542
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
We report a rare case of in vitro fertilisation (IVF) with egg donation complicated by a subarachnoid haemorrhage (SAH). Haemostatic changes related to IVF are known to increase risk of venous thrombosis; however, less is known regarding the risk of arterial events such as cerebrovascular accidents (CVA). Matrix metalloprotease-9 (MMP-9) upregulated in IVF patients may have a role in arterial aneurysm formation, which is the most common cause of SAH. Further research is required to assess the benefit of screening for risk of CVA and the best way to manage this in the IVF population. This may have implications for the ethics of offering certain procedures such as egg donation to women with pre-existing risk factors.
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页数:6
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