γ-amino-β-ketosulfones as chiral educts:: A facile synthesis of enantiopure α-amino ketones

被引：29

作者：

Sengupta, S ^{[1
]}

Sen Sarma, D ^{[1
]}

Mondal, S ^{[1
]}

机构：

[1] Jadavpur Univ, Dept Chem, Calcutta 700032, W Bengal, India

来源：

TETRAHEDRON | 1998年 / 54卷 / 33期

关键词：

D O I：

10.1016/S0040-4020(98)00533-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Starting from 'chiral-pool' derived gamma-amino-beta-ketosulfones, a facile synthesis of enantiopure alpha-amino ketones has been developed via an alpha-alkylation-desulfonation sequence. Extension of this methodology to enantiopure a-acetoxy ketone synthesis,however, have met with limited success. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：9791 / 9798

页数：8

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