γ-amino-β-ketosulfones as chiral educts:: A facile synthesis of enantiopure α-amino ketones

被引：29
作者：
Sengupta, S [1 ]
Sen Sarma, D [1 ]
Mondal, S [1 ]
机构：
[1] Jadavpur Univ, Dept Chem, Calcutta 700032, W Bengal, India
来源：
TETRAHEDRON | 1998年 / 54卷 / 33期
关键词：
D O I：
10.1016/S0040-4020(98)00533-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Starting from 'chiral-pool' derived gamma-amino-beta-ketosulfones, a facile synthesis of enantiopure alpha-amino ketones has been developed via an alpha-alkylation-desulfonation sequence. Extension of this methodology to enantiopure a-acetoxy ketone synthesis,however, have met with limited success. (C) 1998 Elsevier Science Ltd. All rights reserved.
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收藏
页码：9791 / 9798
页数：8
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