Quinolone prophylaxis for bacterial infections in afebrile high risk neutropenic patients

被引：46
作者：
Bucaneve, Giampaolo [1 ]
Castagnola, Elio
Viscoli, Claudio
Leibovici, Leonard
Menichetti, Francesco
机构：
[1] Azienda Osped Perugia, Ist Med Interna & Sci Oncol, Monteluce Policlin, I-06100 Perugia, Italy
[2] Osped G Gaslini, Dipartimento Ematol & Oncol, Unita Malattie Infett, Genoa, Italy
[3] Univ Genoa, Azienda Osped Univ San Martino, Clin Malattie Infett, Genoa, Italy
[4] E Rabin Med Ctr, Dept Med, Petah Tiqwa, Israel
[5] Osped Cisanello, Unita Malattie Infett, Pisa, Italy
来源：
EJC SUPPLEMENTS | 2007年 / 5卷 / 02期
关键词：
neutropenia; acute leukaemia; haematopoietic stem cell transplantation (HSCT); antibiotic prophylaxis; Quinolones Levofloxacin; ciprofloxacin; ofloxacin; norfloxacin;
D O I：
10.1016/j.ejcsup.2007.06.002
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
These recommendations have been developed by an expert panel following an evidence-based search of the literature assessing the role of fluoroquinolones in the prevention of bacterial infection in patients with acute leukaemia or bone marrow transplantation and neutropenia. We present results from a questionnaire on the current practice among experts in Europe, show results of the literature search, review recommendations available from other international guidelines and provide the panel's recommendations. (c) 2007 Elsevier Ltd. All rights reserved.
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收藏
页码：5 / 12
页数：8
相关论文
共 39 条
[11]   Reappraisal with meta-analysis of the addition of gram-positive prophylaxis to fluoroquinolone in neutropenic patients [J].
Cruciani, M ;
Malena, M ;
Bosco, O ;
Nardi, S ;
Serpelloni, G ;
Mengoli, C .
JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (22) :4127-4137
[12]   Antibacterial prophylaxis after chemotherapy for solid tumors and lymphomas [J].
Cullen, M ;
Steven, N ;
Billingham, L ;
Gaunt, C ;
Hastings, M ;
Simmonds, P ;
Stuart, N ;
Rea, D ;
Bower, M ;
Fernando, I ;
Huddart, R ;
Gollins, S ;
Stanley, A .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (10) :988-998
[13]   COMPARISON OF CIPROFLOXACIN, OFLOXACIN AND PEFLOXACIN FOR THE PREVENTION OF THE BACTERIAL-INFECTION IN NEUTROPENIC PATIENTS WITH HEMATOLOGICAL MALIGNANCIES [J].
DANTONIO, D ;
PICCOLOMINI, R ;
IACONE, A ;
FIORITONI, G ;
PARRUTI, G ;
BETTI, S ;
QUAGLIETTA, AM ;
ACCORSI, P ;
DELLISOLA, M ;
FAVALLI, C .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1994, 33 (04) :837-844
[14]   PREVENTION OF BACTERIAL-INFECTION IN NEUTROPENIC PATIENTS WITH HEMATOLOGIC MALIGNANCIES - A RANDOMIZED, MULTICENTER TRIAL COMPARING NORFLOXACIN WITH CIPROFLOXACIN [J].
DELFAVERO, A .
ANNALS OF INTERNAL MEDICINE, 1991, 115 (01) :7-12
[15]   Efficacy of quinolone prophylaxis in neutropenic cancer patients: A meta-analysis [J].
Engels, EA ;
Lau, J ;
Barza, M .
JOURNAL OF CLINICAL ONCOLOGY, 1998, 16 (03) :1179-1187
[16]   Meta-analysis: Antibiotic prophylaxis reduces mortality in neutropenic patients [J].
Gafter-Gvili, A ;
Fraser, A ;
Paul, M ;
Leibovici, L .
ANNALS OF INTERNAL MEDICINE, 2005, 142 (12) :979-995
[17]   ANTIMICROBIAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS [J].
HARTLAPP, JH .
DRUGS, 1987, 34 :131-133
[18]   2002 guidelines for the use of antimicrobial agents in neutropenic patients with cancer [J].
Hughes, WT ;
Armstrong, D ;
Bodey, GP ;
Bow, EJ ;
Brown, AE ;
Calandra, T ;
Feld, R ;
Pizzo, PA ;
Rolston, KVI ;
Shenep, JL ;
Young, LS .
CLINICAL INFECTIOUS DISEASES, 2002, 34 (06) :730-751
[19]   ORAL NORFLOXACIN FOR PREVENTION OF GRAM-NEGATIVE BACTERIAL-INFECTIONS IN PATIENTS WITH ACUTE-LEUKEMIA AND GRANULOCYTOPENIA - A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].
KARP, JE ;
MERZ, WG ;
HENDRICKSEN, C ;
LAUGHON, B ;
REDDEN, T ;
BAMBERGER, BJ ;
BARTLETT, JG ;
SARAL, R ;
BURKE, PJ .
ANNALS OF INTERNAL MEDICINE, 1987, 106 (01) :1-7
[20]   EMERGENCE OF FLUOROQUINOLONE-RESISTANT ESCHERICHIA-COLI AT A CANCER CENTER [J].
KERN, WV ;
ANDRIOF, E ;
OETHINGER, M ;
KERN, P ;
HACKER, J ;
MARRE, R .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (04) :681-687
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