Harnessing solid-state packing for selective detection of chloride in a macrocyclic anionophore

被引：9
作者：
Vonnegut, Chris L. [1 ,2 ]
Shonkwiler, Airlia M. [1 ,2 ]
Zakharov, Lev N. [3 ]
Haley, Michael M. [1 ,2 ]
Johnson, Darren W. [1 ,2 ]
机构：
[1] Univ Oregon, Dept Chem & Biochem, Eugene, OR 97403 USA
[2] Univ Oregon, Inst Mat Sci, Eugene, OR 97403 USA
[3] Univ Oregon, CAMCOR, 1443 East 13th Ave, Eugene, OR 97403 USA
来源：
CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 61期
基金：
美国国家科学基金会;
关键词：
O HYDROGEN-BONDS; DRUG DISCOVERY; ANION; PROTEINS; SERIES; RECEPTORS; SCAFFOLDS; PHOSPHATE; SENSOR; WATER;
D O I：
10.1039/c6cc03795j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report the synthesis of an inherently fluorescent macrocyclic receptor for chloride. The use of a disulphide tether provides for an excellent yield in the macrocyclization step. This compound binds chloride in the solution and solid state, and while unstable over time in aqueous solution, shows a selective response toward chloride over other anions in the solid state due to intermolecular interactions between fluorophore backbones. Surprisingly, the opto-electronic response to anions differs in solution and the films, with a distinct colorimetric response observed only in the film.
引用
收藏
页码：9506 / 9509
页数：4
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