Microbial reduction of ω-bromoacetophenones in the presence of surfactants

被引：34

作者：

Goswami, A ^{[1
]}

Bezbaruah, RL ^{[1
]}

Goswami, J ^{[1
]}

Borthakur, N ^{[1
]}

Dey, D ^{[1
]}

Hazarika, AK ^{[1
]}

机构：

[1] Reg Res Lab, Jorhat 785006, Assam, India

来源：

TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 18期

关键词：

D O I：

10.1016/S0957-4166(00)00341-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Several omega -bromoacetophenone derivatives 6a-f were reduced to (R)-(-)-2-bromo-1-(phenyl/substituted phenyl) ethanol derivatives 7a-f with whole cell biocatalysts in good yields. The enantiomeric excesses were increased to 95% using an anionic surfactant under an inert atmosphere in an aqueous medium. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3701 / 3709

页数：9

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