Sensitive detection of ascorbic acid using screen-printed electrodes modified by electroactive melanin-like nanoparticles

被引：35

作者：

Argoubi, Wicem ^{[1
]}

Rabti, Amal ^{[1
]}

Ben Aoun, Sami ^{[2
]}

Raouafi, Noureddine ^{[1
]}

机构：

[1] Tunis El Manar Univ, Lab Analyt Chem & Electrochem LR99ES15, Dept Chem, Campus Univ Tunis El Manar 2092, Tunis, Tunisia

[2] Taibah Univ, Dept Chem, Fac Sci, POB 30002, Al Madinah Al Munawarah, Saudi Arabia

来源：

RSC ADVANCES | 2019年 / 9卷 / 64期

关键词：

PERFORMANCE LIQUID-CHROMATOGRAPHY; ELECTROCHEMICAL SENSOR; FLUOROMETRIC-DETERMINATION; VITAMIN-C; DOPAMINE; OXIDE;

D O I：

10.1039/c9ra07948c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this work, we report on the design of an enzyme-less sensitive and selective electrochemical electrode for ascorbic acid (AA) detection using a modified screen-printed electrode of melanin-like nanoparticles (Mel-NPs). Cyclic voltammetry shows that the melanin-modified electrode exhibits high electrocatalytic activity for ascorbic acid. The melanin-like nanoparticles serve as a shuttle to transport electrons from ascorbic acid to the electrode surface. The modified electrode is endowed with a large dynamic window ranging from 5 to 500 ppb. The detection and quantification limits were estimated to be 0.07 and 0.23 ppb, respectively. The modified electrode was successfully used to determine AA in human blood serum, urine and saliva with satisfactory recovery levels.

引用

页码：37384 / 37390

页数：7

共 33 条

[1] Portable electrochemical sensor based on 4-aminobenzoic acid-functionalized herringbone carbon nanotubes for the determination of ascorbic acid and uric acid in human fluids [J].