Significant yield improvement in the stereoselective synthesis of allyl cyanides from Baylis-Hillman derivatives in aqueous medium under the influence of the phase-transfer catalyst

被引：14

作者：

Singh, Vijay ^{[1
]}

Pathak, Richa ^{[1
]}

Batra, Sanjay ^{[1
]}

机构：

[1] Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226001, Uttar Pradesh, India

来源：

CATALYSIS COMMUNICATIONS | 2007年 / 8卷 / 12期

关键词：

baylis-hillman; allyl cyanide; NaCN; phase-transfer catalyst; water;

D O I：

10.1016/j.catcom.2007.03.032

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The nucleophilic reaction of NaCN with the acetyl derivative of Baylis-Hillman adducts in the presence of a phase-transfer catalyst in aqueous medium stereo selectively affords the corresponding allyl cyanides in a short period and excellent yields. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：2048 / 2052

页数：5

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