Development of 5-silylethynyl-1,3-dioxolan-4-one as a new prochiral template for asymmetric phase-transfer catalysis

被引：14
作者：
Hashimoto, Takuya [1 ]
Fukumoto, Kazuhiro [1 ]
Abe, Naoyuki [1 ]
Sakata, Kazuki [1 ]
Maruoka, Keiji [1 ]
机构：
[1] Kyoto Univ, Grad Sch Sci, Dept Chem, Sakyo Ku, Kyoto 6068502, Japan
来源：
CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 40期
关键词：
ENANTIOSELECTIVE ALKYNYLATION; CARBONYL GROUPS; ALKYLATION; KETONES; ACID; CONSTRUCTION; ACETYLENES; COMPLEXES; ALDEHYDES; ADDITIONS;
D O I：
10.1039/c0cc02334e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Phase-transfer catalyzed asymmetric alkylation and Michael addition of 5-silylalkynyl-1,3-dioxolan-4-one were developed as a novel strategy to provide highly modular tertiary alpha-alkyla-alpha-hydroxy acids bearing an alkyne moiety.
引用
收藏
页码：7593 / 7595
页数：3
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