A Review of the Antiviral Role of Green Tea Catechins

被引：149
|
作者：
Xu, Jun [1 ]
Xu, Zhao [1 ]
Zheng, Wenming [1 ]
机构：
[1] Henan Agr Univ, Coll Life Sci, 95 Wenhua Rd, Zhengzhou 450002, Henan, Peoples R China
来源：
MOLECULES | 2017年 / 22卷 / 08期
基金：
中国国家自然科学基金;
关键词：
green tea catechins; chronic infectious diseases; antiviral activity; mechanism; HEPATITIS-B-VIRUS; INFLUENZA-A VIRUS; EPIGALLOCATECHIN GALLATE; IN-VITRO; (-)-EPIGALLOCATECHIN GALLATE; MOLECULAR-DYNAMICS; NUTRIENT MIXTURE; TARGET GENES; ZIKA VIRUS; KAPPA-B;
D O I：
10.3390/molecules22081337
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Over the centuries, infectious diseases caused by viruses have seriously threatened human health globally. Viruses are responsible not only for acute infections but also many chronic infectious diseases. To prevent diseases caused by viruses, the discovery of effective antiviral drugs, in addition to vaccine development, is important. Green tea catechins (GTCs) are polyphenolic compounds from the leaves of Camellia sinensis. In recent decades, GTCs have been reported to provide various health benefits against numerous diseases. Studies have shown that GTCs, especially epigallocatechin-3-gallate (EGCG), have antiviral effects against diverse viruses. The aim of this review is to summarize the developments regarding the antiviral activities of GTCs, to discuss the mechanisms underlying these effects and to offer suggestions for future research directions and perspectives on the antiviral effects of EGCG.
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收藏
页数：18
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