Synthesis, analysis and in vitro antibacterial activity of new metal complexes of sulbactam

被引:0
作者
Kostova, IP
Changov, LS
Keuleyan, EE
Gergova, RT
Manolov, II
机构
[1] Chem Pharmaceut Res Inst, Sofia 1756, Bulgaria
[2] Med Univ Sofia, Fac Pharm, Dept Chem, Sofia 1000, Bulgaria
[3] Med Univ Sofia, Chair Microbiol, Sofia 1431, Bulgaria
[4] Med Univ Sofia, Fac Pharm, Dept Ind Pharm, Sofia 1000, Bulgaria
来源
FARMACO | 1998年 / 53卷 / 12期
关键词
beta-lactamase inhibitor; sulbactam; ampicillin; antibacterial activity; metal complexes of sulbactam;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Complexes of copper(II), nickel(II) and iron(III) with beta-lactamase inhibitor sulbactam have been synthesized, characterized and identified by elemental analysis, IR and H-1 NMR spectroscopy. These complexes have been then tested for their in vitro antibacterial activity in combination with ampicillin against various bacterial species. (C) 1998 Elsevier Science S.A. All rights reserved.
引用
收藏
页码:737 / 740
页数:4
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