Cardiac Surgery and Heparin Induced Thrombocytopaenia (HIT): A Case Report and Short Review

被引：7

作者：

McMeniman, W. J. ^{[1
]}

Chard, R. B. ^{[1
]}

Norrie, J. ^{[1
]}

Posen, J. ^{[1
]}

机构：

[1] Sydney Adventist Hosp, Sydney, NSW, Australia

来源：

HEART LUNG AND CIRCULATION | 2012年 / 21卷 / 05期

关键词：

Heparin induced thrombocytopaenia (HIT); Platelet factor4-heparin (PF4-heparin) antibody; Enzyme linked immunoabsorbant assay (ELISA); American College of Chest Physicians (ACCP); Bivalirudin; Cardiopulmonary bypass; CARDIOPULMONARY BYPASS; BIVALIRUDIN; ANTICOAGULATION; MANAGEMENT; STRATEGIES; ANTIBODIES;

D O I：

10.1016/j.hlc.2012.02.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This patient presented for emergency cardiac surgery following two episodes of thrombocytopaenia, one before and one associated with exposure to unfractionated heparin in a seven-week period of intensive care management. Although the diagnosis of heparin induced thrombocytopaenia (HIT) was uncertain on clinical grounds when assessed by current criteria [5,21],. the positive antibody status directed management in accordance with the internationally recognised guidelines published by the American College of Chest Physicians (ACCP) Evidence-based Clinical Practice Guidelines [4]. An alternative anticoagulant to unfractionated heparin was indicated for cardiopulmonary bypass. Bivalirudin was selected because of recent literature supporting its safe use [2,4,6,7,8,9,21]. (Heart, Lung and Circulation 2012;21:295-299) (C) 2012 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier Inc. All rights reserved.

引用

页码：295 / 299

页数：5

共 22 条

[1] Heparin-induced thrombocytopenia [J].