Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir

被引：4
|
作者：
Wada, Tatsuhiko [1 ]
Shimode, Kosuke [1 ]
Hoshiyama, Takayuki [1 ,2 ]
Takayama, Yoko [2 ]
Yamaoka, Kunihiro [1 ]
机构：
[1] Kitasato Univ, Sch Med, Dept Rheumatol & Infect Dis, Sagamihara, Kanagawa, Japan
[2] Kitasato Univ Hosp, Dept Infect Control & Prevent, Sagamihara, Kanagawa, Japan
来源：
FRONTIERS IN MEDICINE | 2020年 / 7卷
关键词：
COVID-19; Lopinavir; Ritonavir; elderly patient; hyponatremia; cruise ship; CORONAVIRUS; SUSCEPTIBILITY; SARS;
D O I：
10.3389/fmed.2020.00241
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Following the first case of Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-Cov-2), in Wuhan, China, in December 2019, it has spread worldwide. An outbreak in Japan occurred on a cruise ship, and this was followed by community-acquired COVID-19. Herein, we report three cases of COVID-19 that presented pneumonia following admission to Kitasato University Hospital. Patients were admitted based on the positive result of real-time reverse transcriptase-polymerase chain reaction (RT-PCR) tests for COVID-19 nucleic acid. All patients were diagnosed as suffering from non-severe COVID-19 pneumonia and were successfully treated with Lopinavir/Ritonavir (LPV/r). LPV/r could be an option for treating non-severe COVID-19 pneumonia in general and even in elderly patients.
引用
收藏
页数：5
相关论文
共 50 条
  • [1] Severe coronavirus disease 2019 (COVID-19) pneumonia patients treated successfully with a combination of lopinavir/ritonavir plus favipiravir: Case series
    Koba, Hayato
    Yoneda, Taro
    Kaneda, Tomoya
    Ueda, Tsukasa
    Kimura, Hideharu
    Kasahara, Kazuo
    CLINICAL CASE REPORTS, 2020, 8 (12): : 3142 - 3147
  • [2] Lopinavir/ritonavir: Repurposing an old drug for HIV infection in COVID-19 treatment
    Magro, Paola
    Zanella, Isabella
    Pescarolo, Marta
    Castelli, Francesco
    Quiros-Roldan, Eugenia
    BIOMEDICAL JOURNAL, 2021, 44 (01) : 43 - 53
  • [3] Lopinavir / ritonavir for COVID-19: A living systematic review
    Verdugo-Paiva, Francisca
    Izcovich, Ariel
    Ragusa, Martin
    Rada, Gabriel
    MEDWAVE, 2020, 20 (06):
  • [4] Population pharmacokinetics of lopinavir/ritonavir in Covid-19 patients
    Alvarez, Jean Claude
    Moine, Pierre
    Davido, Benjamin
    Etting, Isabelle
    Annane, Djillali
    Larabi, Islam Amine
    Simon, Nicolas
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2021, 77 (03) : 389 - 397
  • [5] Retrospective analysis of severe COVID-19 pneumonia patients treated with lopinavir/ritonavir: A comparison with survivor and non-survivor patients
    Ayten, Omer
    Saylan, Bengu
    SOUTHERN AFRICAN JOURNAL OF INFECTIOUS DISEASES, 2020, 35 (01)
  • [6] The comparison of favipiravir and lopinavir/ritonavir combination in COVID-19 treatment
    Cinarka, Halit
    Gunluoglu, Gulsah
    Cortuk, Mustafa
    Yurt, Sibel
    Kiyik, Murat
    Kosar, Filiz
    Tanriverdi, Elif
    Arslan, Melih Akay
    Baydili, Kursad Nuri
    Koc, Aysu Sinem
    Altin, Sedat
    Cetinkaya, Erdogan
    TURKISH JOURNAL OF MEDICAL SCIENCES, 2021, 51 (04) : 1624 - 1630
  • [7] Severe COVID-19 infection in a kidney transplant recipient treated with lopinavir/ritonavir, hydroxychloroquine and dexamethasone
    Suryantoro, Satriyo Dwi
    Thaha, Mochammad
    Pranawa
    Santoso, Djoko
    Mardiana, Nunuk
    Widodo
    Aditiawardana
    Tjempakasari, Artaria
    Ardhany, Ardityo Rahmat
    Pramudya, Dana
    Hertanto, Decsa Medika
    Febriane, Evy
    Meryana
    Angela, Maria
    Muliono, Ari Christy
    Tanuwidjaja, Handoko
    Setiawan, Philia
    Sugiarto, David
    JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, 2021, 15 (09): : 1257 - 1262
  • [8] Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir
    Mas Serrano, Miguel
    Ricardo Perez-Sanchez, Javier
    Portela Sanchez, Sofia
    De la Casa-Fages, Beatriz
    Mato Jimeno, Victor
    Perez Tamayo, Isabel
    Grandas, Francisco
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2020, 415
  • [9] Population pharmacokinetics of lopinavir/ritonavir in Covid-19 patients
    Jean Claude Alvarez
    Pierre Moine
    Benjamin Davido
    Isabelle Etting
    Djillali Annane
    Islam Amine Larabi
    Nicolas Simon
    European Journal of Clinical Pharmacology, 2021, 77 : 389 - 397
  • [10] Comparative effectiveness of Lopinavir/Ritonavir-based regimens in COVID-19
    Qu, Jian
    Li, Guo-Hua
    Wang, Jiao-Jiao
    He, Ge-Fei
    Huang, Juan-Juan
    Chen, Ying
    Qu, Qiang
    Chen, Xiang-Yu
    Lu, Qiong
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2021, 48 (02) : 203 - 210
12345