Portal hypertension and gastrointestinal bleeding

被引:123
作者
Bosch, Jaime [1 ,2 ]
Abraldes, Juan G. [1 ,2 ]
Berzigotti, Annalisa [3 ,4 ]
Garcia-Pagan, Juan Carlos [1 ,2 ]
机构
[1] Univ Barcelona, Hepat Hemodynam Lab, Hosp Clin, IDIBAPS,Liver Unit, Barcelona 08036, Spain
[2] Univ Barcelona, CIBEREHD, Barcelona, Spain
[3] Hosp Clin Barcelona, Ctr Diagnost Imatge, Barcelona 08036, Spain
[4] Univ Bologna, Dept Internal Med, I-40126 Bologna, Italy
关键词
cirrhosis; varices; endoscopic band ligation; TIPS; beta-adrenergic blockers; hepatic venous pressure gradient;
D O I
10.1055/s-2008-1040318
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Variceal bleeding is one of the most serious complications of portal hypertension. The driving force for the development of varices is an increase in portal pressure. As portal hypertension progresses, varices dilate until they finally rupture and bleed. This sequence of events might be prevented by achieving a sufficient decrease in portal pressure or by acting locally at the varices with endoscopic treatments. This article reviews the rationale for the management of portal hypertension and the current recommendations for the prevention and treatment of variceal bleeding.
引用
收藏
页码:3 / 25
页数:23
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