Role of circulating tumor DNA and circulating tumor cells in breast cancer: History and updates

被引：8

作者：

Chedid, Julien ^{[1
]}

Allam, Sabine ^{[2
]}

Chamseddine, Nathalie ^{[1
]}

Bou Zerdan, Maroun ^{[3
]}

El Nakib, Clara ^{[3
]}

Assi, Hazem, I ^{[3
]}

机构：

[1] St George Hosp Univ, Dept Obstet & Gynecol, Med Ctr, Beirut, Lebanon

[2] Univ Balamand, Fac Med, Beirut, Lebanon

[3] Amer Univ Beirut Med Ctr, Naef K Basile Canc Inst, Div Hematol & Oncol, Dept Internal Med, POB 11-0236,Riad El Solh, Beirut 11072020, Lebanon

来源：

SAGE OPEN MEDICINE | 2022年 / 10卷

关键词：

Circulating tumor DNA; cell-free DNA; circulating tumor cells; breast cancer; biomarkers; CA; 15-3; DISEASE PROGRESSION; PROGNOSTIC-FACTORS; PIK3CA MUTATIONS; ESR1; MUTATIONS; LIQUID BIOPSY; FOLLOW-UP; CEA; PLASMA; DIAGNOSIS;

D O I：

10.1177/20503121221077838

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Circulating tumor DNA, cell-free DNA, and circulating tumor cells have been at the epitome of recent research in breast cancer. These forms of liquid biopsies have been used in monitoring disease progression, estimating the risk of relapse, and response to treatment. Much has been done in relation to serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease. Some studies have also explored their use in monitoring treatment response. As the field of liquid biopsies expands, more prospective studies are needed to tailor management in an individualistic approach. In this literature review, the authors explore the multiple uses of circulating tumor DNA and circulating tumor cells in breast cancer.

引用

页数：11

共 86 条

[41] Detection of Tumor PIK3CA Status in Metastatic Breast Cancer Using Peripheral Blood [J].

Higgins, Michaela J. ;

Jelovac, Danijela ;

Barnathan, Evan ;

Blair, Brian ;

Slater, Shannon ;

Powers, Penny ;

Zorzi, Jane ;

Jeter, Stacie C. ;

Oliver, George R. ;

Fetting, John ;

Emens, Leisha ;

Riley, Carol ;

Stearns, Vered ;

Diehl, Frank ;

Angenendt, Philipp ;

Huang, Peng ;

Cope, Leslie ;

Argani, Pedram ;

Murphy, Kathleen M. ;

Bachman, Kurtis E. ;

Greshock, Joel ;

Wolff, Antonio C. ;

Park, Ben H. .

CLINICAL CANCER RESEARCH, 2012, 18 (12) :3462-3469

[42] The predictive and prognostic role of phosphatase phosphoinositol-3 (PI3) kinase (PIK3CA) mutation in HER2-positive breast cancer receiving HER2-targeted therapy: a meta-analysis [J].

Ibrahim, Ezzeldin M. ;

Kazkaz, Ghieth A. ;

Al-Mansour, Mubarak M. ;

Al-Foheidi, Meteb E. .

BREAST CANCER RESEARCH AND TREATMENT, 2015, 152 (03) :463-476

[43] HER2-Positive Circulating Tumor Cells in Breast Cancer [J].

Ignatiadis, Michail ;

Rothe, Francoise ;

Chaboteaux, Carole ;

Durbecq, Virginie ;

Rouas, Ghizlane ;

Criscitiello, Carmen ;

Metallo, Jessica ;

Kheddoumi, Naima ;

Singhal, Sandeep K. ;

Michiels, Stefan ;

Veys, Isabelle ;

Rossari, Jose ;

Larsimont, Denis ;

Carly, Birgit ;

Pestrin, Marta ;

Bessi, Silvia ;

Buxant, Frederic ;

Liebens, Fabienne ;

Piccart, Martine ;

Sotiriou, Christos .

PLOS ONE, 2011, 6 (01)

[44] Actionability of HER2-amplified circulating tumor cells in HER2-negative metastatic breast cancer: the CirCe T-DM1 trial [J].

Jacot, William ;

Cottu, Paul ;

Berger, Frederique ;

Dubot, Coraline ;

Venat-Bouvet, Laurence ;

Lortholary, Alain ;

Bourgeois, Hugues ;

Bollet, Marc ;

Servent, Veronique ;

Luporsi, Elisabeth ;

Espie, Marc ;

Guiu, Severine ;

D'Hondt, Veronique ;

Dieras, Veronique ;

Sablin, Marie-Paule ;

Brain, Etienne ;

Neffati, Souhir ;

Pierga, Jean-Yves ;

Bidard, Francois-Clement .

BREAST CANCER RESEARCH, 2019, 21 (01)

[45]

Joy J.E., 2005, Saving women's lives : strategies for improving breast cancer detection and diagnosis

[46] Circulating Tumor DNA Measurements As Early Outcome Predictors in Diffuse Large B-Cell Lymphoma [J].

Kurtz, David M. ;

Scherer, Florian ;

Jin, Michael C. ;

Soo, Joanne ;

Craig, Alexander F. M. ;

Esfahani, Mohammad Shahrokh ;

Chabon, Jacob J. ;

Stehr, Henning ;

Liu, Chih Long ;

Tibshirani, Robert ;

Maeda, Lauren S. ;

Gupta, Neel K. ;

Khodadoust, Michael S. ;

Advani, Ranjana H. ;

Levy, Ronald ;

Newman, Aaron M. ;

Duehrsen, Ulrich ;

Huettmann, Andreas ;

Meignan, Michel ;

Casasnovas, Rene-Olivier ;

Westin, Jason R. ;

Roschewski, Mark ;

Wilson, Wyndham H. ;

Gaidano, Gianluca ;

Rossi, Davide ;

Diehn, Maximilian ;

Alizadeh, Ash A. .

JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (28) :2845-+

[47]

Laessig D, 2007, ANTICANCER RES, V27, P1963

[48] Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing [J].

Leary, Rebecca J. ;

Sausen, Mark ;

Kinde, Isaac ;

Papadopoulos, Nickolas ;

Carpten, John D. ;

Craig, David ;

O'Shaughnessy, Joyce ;

Kinzler, Kenneth W. ;

Parmigiani, Giovanni ;

Vogelstein, Bert ;

Diaz, Luis A., Jr. ;

Velculescu, Victor E. .

SCIENCE TRANSLATIONAL MEDICINE, 2012, 4 (162)

[49] Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing [J].

Leary, Rebecca J. ;

Kinde, Isaac ;

Diehl, Frank ;

Schmidt, Kerstin ;

Clouser, Chris ;

Duncan, Cisilya ;

Antipova, Alena ;

Lee, Clarence ;

McKernan, Kevin ;

De la Vega, Francisco M. ;

Kinzler, Kenneth W. ;

Vogelstein, Bert ;

Diaz, Luis A., Jr. ;

Velculescu, Victor E. .

SCIENCE TRANSLATIONAL MEDICINE, 2010, 2 (20) :20ra14

[50] Elevated levels of serum tumor markers CA 15-3 and CEA are prognostic factors for diagnosis of metastatic breast cancers [J].

Lee, Jun Sang ;

Park, Seho ;

Park, Ji Min ;

Cho, Jung Hoon ;

Kim, Seung Il ;

Park, Byeong-Woo .

BREAST CANCER RESEARCH AND TREATMENT, 2013, 141 (03) :477-484

← 1 2 3 4 5 6 7 8 9 →