Role of circulating tumor DNA and circulating tumor cells in breast cancer: History and updates

被引：8

作者：

Chedid, Julien ^{[1
]}

Allam, Sabine ^{[2
]}

Chamseddine, Nathalie ^{[1
]}

Bou Zerdan, Maroun ^{[3
]}

El Nakib, Clara ^{[3
]}

Assi, Hazem, I ^{[3
]}

机构：

[1] St George Hosp Univ, Dept Obstet & Gynecol, Med Ctr, Beirut, Lebanon

[2] Univ Balamand, Fac Med, Beirut, Lebanon

[3] Amer Univ Beirut Med Ctr, Naef K Basile Canc Inst, Div Hematol & Oncol, Dept Internal Med, POB 11-0236,Riad El Solh, Beirut 11072020, Lebanon

来源：

SAGE OPEN MEDICINE | 2022年 / 10卷

关键词：

Circulating tumor DNA; cell-free DNA; circulating tumor cells; breast cancer; biomarkers; CA; 15-3; DISEASE PROGRESSION; PROGNOSTIC-FACTORS; PIK3CA MUTATIONS; ESR1; MUTATIONS; LIQUID BIOPSY; FOLLOW-UP; CEA; PLASMA; DIAGNOSIS;

D O I：

10.1177/20503121221077838

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Circulating tumor DNA, cell-free DNA, and circulating tumor cells have been at the epitome of recent research in breast cancer. These forms of liquid biopsies have been used in monitoring disease progression, estimating the risk of relapse, and response to treatment. Much has been done in relation to serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease. Some studies have also explored their use in monitoring treatment response. As the field of liquid biopsies expands, more prospective studies are needed to tailor management in an individualistic approach. In this literature review, the authors explore the multiple uses of circulating tumor DNA and circulating tumor cells in breast cancer.

引用

页数：11

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