Domino reactions for the synthesis of bridged bicyclic frameworks: fast access to bicyclo[n.3.1]alkanes

被引：164

作者：

Ruiz, Miriam ^{[1
]}

Lopez-Alvarado, Pilar ^{[1
]}

Giorgi, Giorgio ^{[1
]}

Carlos Menendez, J. ^{[1
]}

机构：

[1] Univ Complutense Madrid, Fac Farm, Dept Quim Organ & Farmaceut, E-28040 Madrid, Spain

来源：

CHEMICAL SOCIETY REVIEWS | 2011年 / 40卷 / 07期

关键词：

MICHAEL ADDITION; CASCADE REACTIONS; ORGANIC-CHEMISTRY; HIGHLY EFFICIENT; TANDEM; CYCLOADDITION; CONSTRUCTION; ANNULATION; STRATEGY; CONCISE;

D O I：

10.1039/c1cs15018a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the current bid for synthetic efficiency, multiple bond-forming transformations are becoming a key concept in organic synthesis. In this context, domino protocols have become increasingly common in the synthesis of bicyclic systems. This tutorial review aims at providing a short but authoritative overview of this topic, focusing on the preparation of bridged bicyclo[n.3.1] alkane systems, and is organized according to the number of rings created in the key domino process.

引用

页码：3445 / 3454

页数：10

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