Fabrication of Hydrophilic Polymer Nanocontainers by Use of Supramolecular Templates

被引：28
作者：
Samanta, Avik [1 ,2 ,3 ]
Tesch, Matthias [1 ,2 ,3 ]
Keller, Ulrike [4 ]
Klingauf, Juergen [4 ]
Studer, Armido [1 ,2 ,3 ]
Ravoo, Bart Jan [1 ,2 ,3 ]
机构：
[1] Univ Munster, Organ Chem Inst, D-48149 Munster, Germany
[2] Univ Munster, Grad Sch Chem, D-48149 Munster, Germany
[3] Univ Munster, Ctr Soft Nanosci, D-48149 Munster, Germany
[4] Inst Med Phys & Biophys, D-48149 Munster, Germany
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2015年 / 137卷 / 05期
关键词：
AMPHIPHILIC CYCLODEXTRINS; BILAYER VESICLES; DELIVERY-SYSTEM; HOLLOW SPHERES; LIPOSOMES; NANOCAPSULES; ORGANIZATION; RECOGNITION; ASSEMBLIES; MEMBRANES;
D O I：
10.1021/ja511963g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Polymer-shelled vesicles are prepared by using cyclodextrin vesicles as supramolecular templates and an adamantane-functionalized poly(acrylic acid) additive anchored via hostguest recognition, followed by cross-linking of carboxylic acid groups on the polymer. The polymer-shelled nanocontainers are highly stable and effective for encapsulating small hydrophilic molecules. We also show that a hollow cross-linked polymer cage can be obtained after dissolution of the template vesicles. The size and shell thickness of the polymer cage can be tuned by variation of template size and polymer length.
引用
收藏
页码：1967 / 1971
页数：5
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