Left ventricular hypertrophy: renin-angiotensin system role

被引：0
作者：
Ageev, F. T. [1 ]
Ovchinnikov, A. G. [1 ]
Serbul, V. M. [1 ]
Belenkov, Yu. N. [1 ]
机构：
[1] Fed Agcy High Med Technol, Russian Cardiol Sci & Clin Complex, AK Myasnikov Res Inst Clin Cardiol, Moscow, Russia
来源：
CARDIOVASCULAR THERAPY AND PREVENTION | 2008年 / 7卷 / 02期
关键词：
arterial hypertension; left ventricular hypertrophy; renin-angiotensin system; angiotensin receptor blockers; ACE inhibitors;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The review presents modem views on pathogenetic mechanisms of myocardial hypertrophy, with the key role played by renin-angiotensin system (RAS) activation and hemodynamic overload. The authors analyze main structural and functional disturbances typical for and underlying the clinical manifestation of hypertrophy (diastolic dysfunction, myocardial fibrosis). Principal approaches to pharmaceutical correction of myocardial hypertrophy, including RAS blocker therapy, are described.
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收藏
页码：98 / 108
页数：11
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