Adenoma with gastric differentiation (so-called pyloric gland adenoma) in a heterotopic gastric corpus mucosa in the rectum

被引:27
作者
Vieth, M
Kushima, R
de Jonge, JPA
Borchard, F
Oellig, F
Stolte, M
机构
[1] Klinikum Bayreuth, Inst Pathol, D-95445 Bayreuth, Germany
[2] Shiga Univ Med Sci, Dept Clin Sci & Lab Med, Div Diagnost Pathol, Shiga 5202192, Japan
[3] Inst Pathol, D-48529 Nordhorn, Germany
[4] Klinikum Aschaffenburg, Inst Pathol, D-63703 Aschaffenburg, Germany
关键词
pyloric-gland adenoma; rectum polyp; heterotopic gastric mucosa;
D O I
10.1007/s00428-005-1242-2
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
In a 46-year-old man, a pedunculated rectal polyp measuring 3.0x3.0x2.0 cm was diagnosed histologically as a pyloric gland-type adenoma arising in heterotopic gastric corpus mucosa. The luminal site was covered by glands of the gastric foveolar type, displaying focal marked proliferation interpreted as low-grade intraepithelial neoplasia. A bidirectional gastric differentiation was found: most lower glandular structures showed positivity for the deep gastric mucin core protein Muc 6 and superficial positivity for gastric foveolar epithelium mucin core protein Muc 5AC. Pyloric gland adenoma has so far been described in one larger series only and a few case reports of the stomach, gallbladder, pancreatic duct and within heterotopic gastric corpus mucosa of the duodenal bulb. The present case report is the first case of a pyloric gland-type adenoma within a gastric corpus heterotopia of the rectal mucosa.
引用
收藏
页码:542 / 545
页数:4
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