Palliative Radiotherapy for Diffuse Large B-cell Lymphoma

被引：9

作者：

Wright, Christopher M. ^{[1
]}

Koroulakis, Antony I. ^{[2
]}

Baron, Jonathan A. ^{[1
]}

Chong, Elise A. ^{[3
]}

Tseng, Yolanda D. ^{[4
]}

Kurtz, Goldie ^{[1
]}

LaRiviere, Michael ^{[1
]}

Venigalla, Sriram ^{[1
]}

Jones, Joshua A. ^{[1
]}

Maity, Amit ^{[1
]}

Mohindra, Pranshu ^{[2
]}

Plastaras, John P. ^{[1
]}

Paydar, Ima ^{[1
]}

机构：

[1] Univ Penn, Dept Radiat Oncol, 3400 Civ Ctr Blvd, Philadelphia, PA 19104 USA

[2] Univ Maryland, Dept Radiat Oncol, Baltimore, MD 21201 USA

[3] Univ Penn, Lymphoma Program, Abramson Canc Ctr, Philadelphia, PA 19104 USA

[4] Univ Washington, Dept Radiat Oncol, Seattle, WA 98195 USA

来源：

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | 2021年 / 21卷 / 10期

关键词：

Lymphoma; Diffuse large B-cell lymphoma; Palliation; Radiotherapy; Palliative radiotherapy; NON-HODGKINS-LYMPHOMA; LOW-DOSE RADIOTHERAPY; BONE-MARROW-TRANSPLANTATION; WHOLE-BRAIN RADIOTHERAPY; MODERN RADIATION-THERAPY; ORBITAL LYMPHOMA; EXTRANODAL INVOLVEMENT; REFRACTORY PRIMARY; OCULAR ADNEXA; DOUBLE-HIT;

D O I：

10.1016/j.clml.2021.05.007

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Recent improvements in chemoimmunotherapies, targeted agents, hematopoietic stem cell transplants, and cellular therapies have revolutionized treatment paradigms for patients with diffuse large B-cell lymphoma (DLBCL). Even in the relapsed or refractory setting, contemporary treatment options are delivered with curative intent and can lead to lasting remissions. Although such therapies have improved overall outcomes, they have increasingly led to a wide variety of presentations of recurrent tumors in need of palliation. Here, we review the use of radiotherapy (RT) in the palliation of DLBCL. We draw particular attention to the evolving role for hypofractionated RT and low-dose RT for DLBCL. We review the available literature on these topics and focus on commonly encountered clinical scenarios.

引用

页码：650 / 658

页数：9

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